Inflammatory orbital pseudotumor with extension beyond the orbit

Mahr, Michael A.; Salomão, Diva R.; Garrity, James A.

doi:10.1016/j.ajo.2004.04.026

Cited by 55 publications

(27 citation statements)

References 10 publications

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“…Notably, neuroimaging revealed the disease extension, pain was not a unified feature of the disease, all had a non-specific inflammatory pattern, and none of these four patients required non-steroidal immunosuppressive or radiotherapeutic regimens. 99 In contrast, all four patients reported from Australia reported pain as part of their symptom complex, sclerosing inflammation was observed in three patients, and all required radiotherapy or immunosuppression. 100 The choice of MRI or CT is determined both by the clinical features of disease and suspected tissue involvement.…”

Section: Diagnostic Testingmentioning

confidence: 86%

“…99,100 In a series of four patients from the Mayo Clinic, three had associated intracranial extension and one demonstrated maxillary sinus involvement. Notably, neuroimaging revealed the disease extension, pain was not a unified feature of the disease, all had a non-specific inflammatory pattern, and none of these four patients required non-steroidal immunosuppressive or radiotherapeutic regimens.…”

Section: Diagnostic Testingmentioning

confidence: 99%

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Orbital inflammatory disease: a diagnostic and therapeutic challenge

Gordon

2006

Eye

172

115

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Section: Diagnostic Testingmentioning

confidence: 86%

Section: Diagnostic Testingmentioning

confidence: 99%

Orbital inflammatory disease: a diagnostic and therapeutic challenge

Gordon

2006

Eye

172

115

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show abstract

“…Erişkinlerde daha çok karşımıza propitozis gözlemlenirken çocuklarda ise daha çok pitoz olarak görülür (5). Histopatolojik olarak değişken derecelerde fibrozis ile birlikte değişken derecede polimorfik lenfosit infiltrasyon görülür (6). İdiyopatik orbital miyozit kesin nedeni bilinmesede en çok immünolojik mekanizmalar suçlanmaktadır (7).…”

Section: Introductionunclassified

Idiopathic orbital myositis in a pediatric patient and treatment

Capkin¹,

Bilak²,

Bi̇lgi̇n³

et al. 2017

Eur J Ther

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hastalıktır. Dokuz yaşında erkek hasta, 3 gün önce başlayan sola bakışta ağrı ve çift görme şikayeti ile kliniğimize başvurdu. Göz hareketleri muayenesinde sol gözde sola bakış kısıtlılığı ve diplopi mevcuttu. Her iki gözde göz hareketleri diğer bakış yönlerine normaldi. Sol göz kapağında minimal ödem tespit edildi. İdiyopatik orbital miyozit, tiroid oftalmopati, orbital sellülit ön tanısı ile orbital manyetik rezonans görüntüleme (MRG) istendi. Orbital MRG sol medial rektus kasında belirgin kalınlaşma tespit edildi. Tiroide fonksiyon testlerinin normal sınırda olması ile tiroid oftalmopatisi dışlandı ve orbital MRG'de; orbital apse ve sinüzit bulgusuna ve sol medial rektus kası dışında ekstraoküler infiltrasyona rastlanmaması nedeniyle de orbital sellülit dışlandı. İdiyopatik orbital miyozit tanısı konularak 30 mg/gün oral prednizolon tedavisi başlandı. Birinci haftanın sonunda diplopi ve sola hareket bakış kısıtlılığı tamamen düzelmişti. Akut ağrı ile başlayan oküler hareket kısıtlılığı ve diplopi gözlenen idiyopatik orbital miyozit, nonspesifik orbital inflamasyon (NSOİ)'nun bir alt grubu olarak çocuk hastalarda nadiren görülmekte ve kolaylıkla atlanabilmektedir. Dikkatli bir muayene ve MRG görüntüleme sisteminin sayesinde orbital miyozit düşü-nülmesi gereken tanılardan biri olmalıdır. Böylelikle gecikmiş tanı ve ihtiyaç olmayan antibiyotik kullanımı ve gereksiz biyopsi önle-nebilir. Anahtar Kelimeler: Orbital miyozit, MR görüntüleme, prednizolon ABSTRACTIdiopathic orbital myositis is an autoimmune orbital disease characterized by one or more non-granulomatous, non-infectious, non-neoplastic extraocular muscle inflammation whose etiology was unknown. A 9-year-old male patient was admitted to our clinic with diplopia and a pain in left-gaze starting 3 days ago. There was a restriction in left-gaze in the left eye and diplopia in the examination of eye movements. The other gaze direction were normal in both eyes movements. Minimal edema was also detected in the left eyelid. Orbital MRI was asked for the preliminary diagnosis of idiopathic orbital myositis, thyroid eye disease, and orbital cellulitis. It was a marked thickening detected in the orbital MRI left medial rectus muscle. Owing to thyroid function tests are in the normal range thyroid ophthalmopathy were excluded and in orbital MRI; Orbital cellulitis were excluded because of the fact that there were no orbital abscess and sinusitis findings and also no extra-ocular infiltration outside the left medial rectus muscle. 30 mg/day of oral prednisolone therapy was started after diagnosing with idiopathic orbital myositis. At the end of the first week, the restriction in left-gaze and the diplopia was completely improved. Ocular movement limitation starting with acute pain and diplopia are rarely seen in pediatric patients and can easily be overcome as a subgroup of the observed idiopathic orbital myositis and the non-specific orbital inflammation (NSOI). Thanks to a careful examination and MRI imaging system, orbital myositis should be one of the diagnoses ...

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“…This tumor may be indistinguishable from idiopathic inflammatory pseudotumor by imaging (Fig 13). 62,63 Idiopathic Hypertrophic Pachymeningitis Idiopathic hypertrophic cranial pachymeningitis is a rare inflammatory disease with diffuse dural involvement that may extend to the CS. MR imaging shows enhancement and dural thickening, which may be extensive or more localized (Fig 14).…”

Section: Inflammatory Myofibroblastic Tumormentioning

confidence: 99%

Imaging Lesions of the Cavernous Sinus

Razek¹,

Castillo²

2008

AJNR Am J Neuroradiol

120

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SUMMARY:Our aim was to review the imaging findings of relatively common lesions involving the cavernous sinus (CS), such as neoplastic, inflammatory, and vascular ones. The most common are neurogenic tumors and cavernoma. Tumors of the nasopharynx, skull base, and sphenoid sinus may extend to the CS as can perineural and hematogenous metastases. Inflammatory, infective, and granulomatous lesions show linear or nodular enhancement of the meninges of the CS but often have nonspecific MR imaging features. In many of these cases, involvement elsewhere suggests the diagnosis. MR imaging is sensitive for detecting vascular lesions such as carotid cavernous fistulas, aneurysms, and thromboses.

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Inflammatory orbital pseudotumor with extension beyond the orbit

Cited by 55 publications

References 10 publications

Orbital inflammatory disease: a diagnostic and therapeutic challenge

Orbital inflammatory disease: a diagnostic and therapeutic challenge

Idiopathic orbital myositis in a pediatric patient and treatment

Imaging Lesions of the Cavernous Sinus

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