Inflammatory myofibroblastic tumor of the trachea

Boloursaz, Mohammad Reza; Khalilzadeh, Soheila; Dezfoli, Azizollah Abbasi; Kahkoee, Shahram; Karimi, Shirin; Abbaszadeh, Mohammad; Masjedi, Mohammad Reza; Velayati, Ali Akbar

doi:10.1007/s00383-011-2851-2

Cited by 9 publications

(8 citation statements)

References 9 publications

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“…Although there are some reports on IMTs being managed with therapeutic bronchoscopy alone, 2,14,26,41,53,54 we found at least 5 instances in which bronchoscopy had to be followed up with surgery for either complete removal or recurrence (Tables 1, 2). 31,36,44,47 Thus, therapeutic bronchoscopy has a limited role in management of these tumors. In patients presenting acutely with respiratory symptoms, the rigid bronchoscope can be used to debulk the tumor for relief of airway obstruction, as was done in our case.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory Myofibroblastic Tumor of the Trachea in the Pediatric Age Group

Jindal¹,

Bal²,

Agarwal³

2015

Journal of Bronchology &Amp; Interventional Pulmonology

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Inflammatory myofibroblastic tumors are uncommon tumors, which present as solitary masses in the pulmonary parenchyma. Tracheal involvement by these tumors is extremely rare and can be misdiagnosed as asthma. The closest histologic differential diagnoses are IgG4-related sclerosing pseudotumors, which are differentiated by IgG4 positivity. Fifty percent of inflammatory myofibroblastic tumors are positive for anaplastic lymphoma kinase gene rearrangements. The treatment modality of choice is surgical resection with therapeutic bronchoscopy reserved for patients presenting with acute airway obstruction or in those unwilling for surgery. New and upcoming treatments include anaplastic lymphoma kinase inhibitors like crizotinib.

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Section: Discussionmentioning

confidence: 99%

Inflammatory Myofibroblastic Tumor of the Trachea in the Pediatric Age Group

Jindal¹,

Bal²,

Agarwal³

2015

Journal of Bronchology &Amp; Interventional Pulmonology

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“…The lungs are the organs in which these masses have been most commonly reported in the literature . Extrapulmonary presentation of these tumors is uncommon but has been described in such sites as the brain, trachea, breast, spleen, and the kidneys . The gastrointestinal tract can also be involved, with a variety of case reports of these masses in the liver, stomach, colon, and the Vater's ampulla .…”

Section: Introductionmentioning

confidence: 99%

Inflammatory myofibroblastic tumor of the esophagus treated by endoscopy

et al. 2012

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Inflammatory myofibroblastic tumors are rare lesions that have been described in virtually every organ including the gastrointestinal tract. The esophagus is an extremely unusual site for these tumors, with only a few cases described in the literature. Surgery has been the most common therapeutic approach used for the resection of these lesions. In the present case, a patient diagnosed with an inflammatory myofibroblastic tumor of the upper esophagus was reported, and it was successfully removed by endoscopy with no complications.

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“…The recurrence of tracheal IMT was also seen in a 2-year-old child who was symptomatic 3 months after excision of the initial lesion. 12 It is important to note that in our case the recurrence was noticed due to the abnormal curve (Fig. 2B) on spirometry six months after the initial excision although the patient was asymptomatic.…”

Section: Discussionmentioning

confidence: 51%

Flow-volume curve in the diagnosis and follow-up of intrathoracic airway obstruction

et al. 2017

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Spirometry is an easy method to measure lung function and to show pathophysiology. It assists not only to determine the severity of bronchial obstruction in asthma but also to differentiate the characteristics of the intrathoracic diseases narrowing the central airways. Different types of benign and malignant tumors of the trachea may cause emergence of symptoms of airway obstruction. Herein a patient who had been initially diagnosed with asthma but later on shown to have intratracheal myofibroblastic tumor is presented. The importance of flow-volume curve in both initial diagnosis of the mass and in the detection of recurrence is discussed.

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Inflammatory myofibroblastic tumor of the trachea

Cited by 9 publications

References 9 publications

Inflammatory Myofibroblastic Tumor of the Trachea in the Pediatric Age Group

Inflammatory Myofibroblastic Tumor of the Trachea in the Pediatric Age Group

Inflammatory myofibroblastic tumor of the esophagus treated by endoscopy

Flow-volume curve in the diagnosis and follow-up of intrathoracic airway obstruction

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