Inflammatory Myofibroblastic Tumor of the Kidney

Jenkins, Lawrence C.; Whittington, Elizabeth; Ciancio, Gaetano; Jordà, Mercè

doi:10.1016/j.juro.2013.03.036

Cited by 3 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At the same time, we found that the significant inflammatory cell types of IMTs included neutrophil, eosinophil, plasma cell, and lymphocyte, which supported the prior reports [10] . According to the current WHO Classification of Tumors of Soft tissue and Bone [11] , moreover, The first case report of IMTs of the kidney was published in 1976, closely followed by a series of case reports and rare studies [9,[12][13][14][15][16] . The median age of kidney IMTs 39 years (range 6-74 years) in our study doesn't consist with the mean age 57.1 years in a large study [9] , but consists with the mean age 43.3 years of literatures review in the 13 case reports.…”

Section: Discussionmentioning

confidence: 99%

Multi-centers clinicopathological prognosis study of inflammatory myofibroblastic tumors of urogenital system in China

Chen

Cao

et al. 2019

Preprint

View full text Add to dashboard Cite

KEYWORDSInflammatory myofibroblastic tumors, Urogenital system, Kidney, Urinary bladder 3 Abstract Purpose: We aimed at investigate a series of inflammatory myofibroblastic tumors (IMTs) of urogenital system in multi-centers in China. Materials and methods: Within the pathologic databases at West China Hospital of Sichuan University and the Third People's Hospital of Chengdu, we identified 33 individuals with IMTs from May 2009 to January 2019 Results: A total of 33 patients with IMTs of urogenital system were identified. The median age of all the individuals was 39.5 years (range 0-74

show abstract

Section: Discussionmentioning

confidence: 99%

Multi-centers clinicopathological prognosis study of inflammatory myofibroblastic tumors of urogenital system in China

Chen

Cao

et al. 2019

Preprint

View full text Add to dashboard Cite

show abstract

“…Most renal IMT cases have undergone surgical resection, and nephrectomy is usually performed due to the mimicry of malignancy on imaging findings, such as renal carcinoma or Wilms tumor. 5 , 15 , 21 , 22 In some cases that were not treated by resection, corticosteroid therapy was somewhat beneficial. 9 , 10 In our case, because the preoperative imaging was similar to cystic renal cell carcinoma, surgical resection was implemented, and no recurrence was observed during follow-up.…”

Section: Discussionmentioning

confidence: 99%

A Renal Inflammatory Myofibroblastic Tumor Similar to Cystic Renal Cell Carcinoma

Liang

2015

Medicine

View full text Add to dashboard Cite

We describe and analyze the clinical course and imaging findings of a case of a renal inflammatory myofibroblastic tumor (IMT) that is similar to cystic renal cell carcinoma.“Solitary cysts” on the left kidney were found during a health examination of a 60-year-old female. The patient also had hypertension. She had undergone surgeries twice for limb trauma fracture and had no definite record of hepatitis. There was no tenderness with percussion of the kidney area or edema in the lower extremity. The renal function results, including serum creatinine, blood urea nitrogen, and blood urea, were within the normal range. No gross hematuria or microscopic hematuria was found. An 8.7 cm × 9.2 cm mixed echogenic mass at the upper pole of the left kidney was observed with ultrasound, the majority of which was an anechoic mass that was slightly protruding from the renal capsule and had well-circumscribed borders. After a bolus injection of an ultrasound contrast agent, the mass had rapid enhancement with fast fading. An approximately 9.4 cm × 10.1 cm round-like cyst lesion at the upper pole of the left kidney was revealed by computed tomography (CT) examination of the abdomen; it had edge finishing with well-circumscribed borders. The upper inner wall of the lesion was thick with crescentic soft tissue. The solid content had gradual enhancement on enhanced CT scans. A kidney tumor was considered based on the CT findings.Based on the preoperative examination, the left renal cystic masses were resected. Intraoperative frozen sections were used to further clarify the nature of the lesion, and no significant malignant cells were observed; therefore, the kidney was not removed. The pathological diagnosis was renal IMT. After surgery, the patient recovered and did not have recurrence or metastasis over the course of long-term follow-up.CT images of our patient with renal cystic disease are categorized as Fuhrman grade IV and typically indicate the presence of malignant lesions. However, gradual enhancement of the solid content in our case is different from typical cystic renal cell carcinoma. The nature of the lesion was further identified using intraoperative frozen sections, which helped avoid unnecessary nephrectomy.

show abstract

“…Histopathological examination of an IMT reveals a wide spectrum, but characteristically includes proliferation of spindle cells. There is typically an infiltrate of mixed cell types including plasma cells, histiocytes, lymphocytes, and eosinophils, amongst others [2,[4][5][6]14]. Histologically, three patterns, which can occur in combination with each other, have been described.…”

Section: Discussionmentioning

confidence: 99%