Inflammatory Myofibroblastic Tumor of the Colon with an Unusual Presentation of Intestinal Intussusception

Abstract

Inflammatory myfibroblastic tumor (IMT), also known as inflammatory pseudotumor is unusual, benign solid tumor. This tumor is commonly reported in the lungs but can be present in extrapulmonary sites as well. We present the case of a 7-year-old girl with IMT in an unusual location. The patient was admitted with abdominal pain, and ultrasound showed a solid mass in the abdomen. She was operated and colocolic intussusception secondary to a mass was found. Histologic evaluation of mass revealed IMT.

Inflammatory myofibroblastic tumor of the small intestine mimicking acute appendicitis: a case report and review of the literature

“…The lung is the most commonly affected site, but extrapulmonary IMT may include the mesentery-omentum, upper respiratory tract, genitourinary tract, retroperitoneum, pelvis, head, neck, spleen, brain, pancreas, liver, and gastrointestinal tract [4, 6]. Documented IMT cases in the mesentery-omentum have been located mostly in the mesentery of the small bowel and not in the antimesenteric edge, as was the case in our patient [7].…”

“…Rarely, the presentation may be complicated by an intestinal obstruction, intussusception, or acute abdomen mimicking acute appendicitis, as was the case in our patient [2]. Laboratory abnormalities are present in a minority of patients and include hypochromic microcytic anemia, as in our patient; increased serum immunoglobulins; and elevated thrombocyte counts [2, 6, 7]. Leukocytosis, as in our patient, is a rare hematologic finding that should be included in the list of laboratory abnormalities [1, 2].…”

“…IMT was first described in 1937 as a lung tumor and is more common in children and young adults [4, 6]. IMT is a rare lesion that belongs to the group of soft tissue tumors.…”

“…The etiologic factors responsible for the development of IMT are not clearly established [1–3, 6]. IMT may represent an immunologic response to an infectious or noninfectious agent, or it may be a true tumor.…”

“…The lung is the most commonly affected location, but lesions have been reported in a variety of intraabdominal organs [3, 6, 7]. However, small bowel tumors are particularly rare, and even more rarely they are located in the antimesenteric edge of the small bowel [7].…”