Inflammatory Bowel Disease and Pericarditis

Rheingold, Owen J.

doi:10.7326/0003-4819-82-4-592_1

Cited by 25 publications

(9 citation statements)

References 3 publications

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“…Third, this case report confirms and extends eight previous cases of pericardial tamponade associated with ulcerative colitis ( [20][21][22][23][24][25][26][27]; Table 1), and one case associated with Crohn's colitis [28]. In the currently reported case pericardiectomy reversed the life-threatening cardiac tamponade from the pericarditis [29,30].…”

Section: Discussionsupporting

confidence: 89%

Chronic Pericarditis and Pericardial Tamponade Associated with Ulcerative Colitis

Cappell¹,

Turkieh

2007

Dig Dis Sci

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Unlike other extraintestinal inflammatory manifestations of ulcerative colitis, cardiac involvement is infrequently reported and inadequately characterized, with only 9 previously reported cases of pericardial tamponade associated with inflammatory bowel disease. A 32 year old male with ulcerative colitis, treated with orally administered mesalamine for ten years, developed chronic pericarditis. Extensive clinical and laboratory evaluation failed to find any cause of the pericarditis other than the ulcerative colitis. Although the pericarditis remitted with indomethacin therapy, this medicine had to be discontinued because of a reactivation of ulcerative colitis attributed to this nosteroidal antiinflammatory drug (NSAID). The pericarditis then responded well to high-dose corticosteroid therapy, but the patient represented with chest pain, dyspnea, tachypnea, and engorged neck veins after tapering the corticosteroid therapy. Angiography revealed near equalization of end diastolic pressures in both ventricles, a finding consistent with pericardial tamponade. The patient underwent subtotal pericardiectomy. Thoracotomy revealed a thickened pericardial wall and a large pericardial effusion. The patient's symptoms resolved postpericardiectomy. This case extends the clinical spectrum of pericarditis associated with ulcerative colitis, by describing a case of pericarditis that was chronic, refractory to maintenance medical therapy, caused pericardial tamponade, and was successfully treated by pericardiectomy.

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Section: Discussionsupporting

confidence: 89%

Chronic Pericarditis and Pericardial Tamponade Associated with Ulcerative Colitis

Cappell¹,

Turkieh

2007

Dig Dis Sci

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“…In any event, as in the majority of the previously reported cases, high dose systemic corticosteroid treatment resulted in a rapid resolution of the pericarditis. Although pericardial effusion and even tamponade have been described in other patients (Breitenstein et al, 1974;Rheingold, 1975), no fluid accumulation was demonstrated in this case and no additional therapy was required. Some previous reports suggest that relapse may not be uncommon in patients with pericarditis and inflammatory bowel disease (Goodman et al, 1976).…”

Section: Discussionmentioning

confidence: 51%

Crohn’s disease and pericarditis

Manomohan¹,

Subbuswamy²,

Willoughby³

1984

Postgraduate Medical Journal

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Summary A patient is described who developed acute pericarditis during a severe first attack of Crohn’s disease. The opportunity was taken to measure levels of circulating immune complexes, both during the acute phase of the illness and during convalescence; no significant change in these levels from normal values was found. The Crohn’s disease and the associated pericarditis responded to systemic corticosteroid therapy, and no relapse has occurred during 14 months of follow-up.

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“…Pericarditis rarely has been reported in association with IBD. [63][64][65][66][67][68] It did not get mentioned in a recent review of rare extraintestinal manifestations of IBD. 69 Although the PR was increased in both UC and Crohn's disease patients over the general population, the actual prevalence of the condition was quite low.…”

Section: Discussionmentioning

confidence: 99%