Crohn’s disease and pericarditis

Manomohan, V.; Subbuswamy, S. G.; Willoughby, C P

doi:10.1136/pgmj.60.708.682

Cited by 13 publications

(5 citation statements)

References 9 publications

(10 reference statements)

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“…In this patient, the pericarditis responded twice to highdose prednisone administration, but recurred both times when the prednisone dose was tapered. This phenomenon has been previously reported [18,19].…”

Section: Discussionsupporting

confidence: 87%

Chronic Pericarditis and Pericardial Tamponade Associated with Ulcerative Colitis

Cappell¹,

Turkieh

2007

Dig Dis Sci

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Unlike other extraintestinal inflammatory manifestations of ulcerative colitis, cardiac involvement is infrequently reported and inadequately characterized, with only 9 previously reported cases of pericardial tamponade associated with inflammatory bowel disease. A 32 year old male with ulcerative colitis, treated with orally administered mesalamine for ten years, developed chronic pericarditis. Extensive clinical and laboratory evaluation failed to find any cause of the pericarditis other than the ulcerative colitis. Although the pericarditis remitted with indomethacin therapy, this medicine had to be discontinued because of a reactivation of ulcerative colitis attributed to this nosteroidal antiinflammatory drug (NSAID). The pericarditis then responded well to high-dose corticosteroid therapy, but the patient represented with chest pain, dyspnea, tachypnea, and engorged neck veins after tapering the corticosteroid therapy. Angiography revealed near equalization of end diastolic pressures in both ventricles, a finding consistent with pericardial tamponade. The patient underwent subtotal pericardiectomy. Thoracotomy revealed a thickened pericardial wall and a large pericardial effusion. The patient's symptoms resolved postpericardiectomy. This case extends the clinical spectrum of pericarditis associated with ulcerative colitis, by describing a case of pericarditis that was chronic, refractory to maintenance medical therapy, caused pericardial tamponade, and was successfully treated by pericardiectomy.

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Section: Discussionsupporting

confidence: 87%

Chronic Pericarditis and Pericardial Tamponade Associated with Ulcerative Colitis

Cappell¹,

Turkieh

2007

Dig Dis Sci

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“…Primary cardiac abnormalities in IBD are very rare, and almost all information is limited to case reports describing conduction problems43,44 or pericarditis with or without pericardial effusion and myocardial involvement 45–53. 5‐Aminosalicylic acid drugs used in the treatment of IBD have been implicated as causing pericarditis and myocarditis as well 54,55…”

Section: The Systemic Vasculature In Ibdmentioning

confidence: 99%

the Vasculature and Inflammatory Bowel Disease. Contribution to Pathogenesis and Clinical Pathology

Hatoum

Binion

2005

Inflammatory Bowel Diseases

127

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“…reported an adolescent with severe pericarditis with flare-up of Crohn's disease. [ 14 ] In contrast to the above-mentioned studies, we present a case, in which our patient displayed recurrent pericarditis in the setting of established Crohn's colitis during prolonged remission. A similar case has been reported in an adult with recurrent myopericarditis in the setting of Crohn's disease and association with human lymphocyte antigen B27-positive.…”

Section: Discussionmentioning

confidence: 74%

Recurrent pericarditis in an adolescent with Crohn's colitis

2020

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Extraintestinal manifestations are common complications of inflammatory bowel disease (IBD), whereas the recurrent pericarditis during remission of Crohn's disease is rarely reported. Chest pain developed in a 13-year-old adolescent male who had a history of Crohn's colitis since 9 years of age and was in remission for 4 years after treatment with infliximab, adalimumab, and vedolizumab. Physicians should be aware of the pericardial involvement in patients with a history of IBD. The literature on pericardial involvement in Crohn's disease is reviewed with emphasis on the management of recurrent pericardial effusion in the pediatric age group.

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Crohn’s disease and pericarditis

Cited by 13 publications

References 9 publications

Chronic Pericarditis and Pericardial Tamponade Associated with Ulcerative Colitis

Chronic Pericarditis and Pericardial Tamponade Associated with Ulcerative Colitis

the Vasculature and Inflammatory Bowel Disease. Contribution to Pathogenesis and Clinical Pathology

Recurrent pericarditis in an adolescent with Crohn's colitis

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