2018
DOI: 10.18632/aging.101575
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Abstract: The neutrophil-to-lymphocyte ratio (NLR) and red blood cell distribution width (RDW) are important indicators of adverse outcomes and have predictive value for many diseases; however, the relationships between frailty, and the NLR and RDW in patients with coronary heart disease (CHD) have not been determined. In this cross-sectional study, we investigated the association between frailty, and the NLR and RDW in elderly CHD patients ≥ 60 years of age. Frailty was defined according to frailty phenotype. Of 345 pa… Show more

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Cited by 27 publications
(26 citation statements)
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References 40 publications
(46 reference statements)
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“…Hemogram-derived infl ammatory markers were also studied in frailty. Authors reported that NLR and red cell distribution width were weakly correlated with frailty in subjects with coronary heart disease (15). In another study, it was concluded that in patients with cancer, the NLR was correlated with Carolina Frailty index, another scale for determining frailty (16).…”
Section: Discussionmentioning
confidence: 99%
“…Hemogram-derived infl ammatory markers were also studied in frailty. Authors reported that NLR and red cell distribution width were weakly correlated with frailty in subjects with coronary heart disease (15). In another study, it was concluded that in patients with cancer, the NLR was correlated with Carolina Frailty index, another scale for determining frailty (16).…”
Section: Discussionmentioning
confidence: 99%
“…Albumin was measured using dye binding BCG . Haemoglobin, red blood cell width (RDW) and absolute neutrophil counts, measured by Sysmex's multiple methods, have been linked with inflammation and immunosenescence . Fasting plasma glucose was measured by the glucose oxidase method in the morning after at least 10 h overnight fast .…”
Section: Methodsmentioning
confidence: 99%
“…This background clearly demonstrates an association of NLR with the cancer immune environment; consequently, NLR is considered to be related with the clinical outcome. The present nding that NLR may be a speci c prognostic factor of OS in elderly patients with GC indicates that NLR might not only re ect the tumor environment but may also be associated with host frailty [30,31]. Frailty is a syndrome affecting physiologic reserves across multiple organ systems and has been identi ed as a poor prognostic factor in geriatric oncology [32,33].…”
Section: Discussionmentioning
confidence: 84%