Inflammation. A Review of the Process

Trowbridge, Henry O.; Emling, R C; Fornatora, Maria

doi:10.1097/00008505-199700630-00025

Cited by 55 publications

(65 citation statements)

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“…Since the effects of the released NO remain localized near the coating/blood or tissue interface, the potentially detrimental side effects encountered in other systemically administered therapies can be prevented (Kelm and Schrader, 1988;Kelm and Yoshida, 1996). NO released from the coatings on implants may also enhance wound healing (Trowbridge and Emling, 1997) and promote angiogenesis (Ziche et al, 1994;Fukumura and Jain, 1998).…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and bactericidal activity of nitric oxide-releasing natural zeolite

Narin

Albayrak

Ülkü

2010

Applied Clay Science

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The zeolitic tuff from Gördes (Western Anatolia) was used as adsorbent for nitric oxide (NO) storage and release purposes. The NO loading of the zeolite was performed under 20 mL min − 1 NO flow at 30°C and then the zeolite was purged with inert gas in order to remove the species that were reversibly adsorbed and in the gas phase (desorption). The total and reversible adsorption capacities of the zeolite were determined from the adsorption and desorption breakthrough curves, respectively. The NO-loaded zeolite exhibited antibacterial and bactericidal activities against Gram-negative (Escherichia coli) and Gram-positive bacteria (Bacillus subtilis) under physiological conditions. From the NO release kinetics, the diffusion coefficient of NO in the zeolite particle was determined.

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Section: Introductionmentioning

confidence: 99%

Antibacterial and bactericidal activity of nitric oxide-releasing natural zeolite

Narin

Albayrak

Ülkü

2010

Applied Clay Science

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“…Normal : normal SD rat. [24][25][26] . 이렇 게 면역세포를 활성화시켜 NO, PGE2, TNF-α, IL-1β 및 IL-6, IL-10과 같은 염증 매개 물질이 생성되게 한다 27,28) .…”

Section: ) 조직학적 분석unclassified

The Effect of Phaseoli Semen Herbal-acupuncture at KI10 in Lipopolysaccharide Induced Acute Nephritis in Rats

Kwak¹,

Kang²,

Lee³

2013

The Acupuncture

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Objectives : This study was designed to evaluate the effects of Phaseoli Semen Herbalacupuncture(PS-HA) at KI10 in acute nephritis induced by lipopolysaccharide(LPS) in rat. Methods : The rats were divided into 5 groups, which were control, LPS, PS-HA, NP and saline group. LPS, PS-HA, NP and saline groups were given LPS to induce acute nephritis and control group did not receive LPS. LPS group did not receive any treatment after the onset of acute nephritis. PS-HA, NP and saline group received PS-HA, normal acupuncture, and saline injection at KI10 three times per week, respectively. To evaluate the effect of PS-HA at KI10, the complete blood count, BUN, creatinine, TNF-α, and CINC-1 in serum were measured. To show its effect on renal function, creatinine, and total protein in urine was measured as well as urine output. The level of myeloperoxidase in renal tissue was quantified and complete histology was done in kidney samples obtained from the rats. Results : PS-HA group showed a significant reduction in the proportion of WBC and neutrophil, serum BUN, TNF-a, and CINC-1 compared to LPS group. Furthermore, a significant increase in urine output and a decrease in urinary creatinine level, MPO in renal tissue, and number of neutrophils at glomerulus was observed in PS-HA group compared to LPS group Conclusions : PS-HA at KI10 was shown to have a significantly effect on treating LPS induced acute nephrits. Therefore, future study is needed to further evaluate the clinical usefulness of PS-HA at KI10 in treating acute nephritis.

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“…Host defense mechanisms against bacteria emanating from the root canal appear to be the most important factor involved in pus formation associated with abscesses. Formation of oxygen-derived free radicals, such as superoxide and hydrogen peroxide, alongside the release of lysosomal enzymes by polymorphonuclear leukocytes, gives rise to destruction of the connective extracellular matrix, leading to pus formation (13). Therefore, bacteria can exert indirect destructive effects, which seem to be even more significant in the tissue damage associated with acute and chronic apical periodontitis lesions.…”

Section: Endodontic Pathogens and Mechanisms Of Pathogenicitymentioning

confidence: 99%

Bacterial pathogenesis and mediators in apical periodontitis

2007

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Apical periodontitis is a group of inflammatory diseases caused by microorganisms (mainly bacteria) infecting the necrotic root canal system. The pathogenesis of different types of apical periodontitis and even the same type in different individuals is unlikely to follow a stereotyped fashion with regard to the involved bacterial mediators. Disease pathogenesis is rather complex and involves a multitude of bacteria-and host-related factors. This review article discusses the bacterial pathogenesis of acute and chronic apical periodontitis, with the main focus on the bacterial mediators conceivably involved in the different stages of the infectious process, including secreted products (enzymes, exotoxins, N-formyl-methionyl-leucyl-phenylalanine peptides, heat-shock proteins and metabolic end-products) and structural components (lipopolysaccharide, peptidoglycan, lipoteichoic acid, lipoproteins, fimbriae, flagella, outer membrane proteins and vesicles, DNA, and exopolysaccharides). Knowledge of the bacterial factors involved in the pathogenesis of apical periodontitis is important to the understanding of the disease process and to help establishing proper therapeutic measures to inactivate this bacterial "artillery".

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Inflammation. A Review of the Process

Cited by 55 publications

References 0 publications

Antibacterial and bactericidal activity of nitric oxide-releasing natural zeolite

Antibacterial and bactericidal activity of nitric oxide-releasing natural zeolite

The Effect of Phaseoli Semen Herbal-acupuncture at KI10 in Lipopolysaccharide Induced Acute Nephritis in Rats

Bacterial pathogenesis and mediators in apical periodontitis

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