People often make inferences with incomplete information. Previous research has led to a mixed picture of how people treat missing information. To explain these results, the authors follow the Brunswikian perspective on human inference and hypothesize that the mechanism's accuracy for treating missing information depends on how it is distributed in a certain environment. The hypoth-esis is supported by the results of a simulation study, which also shows that the mechanism for treating missing information has a much stronger impact on overall accuracy than the most accurate inference strategies considered. The conclusion is that how people react to missing information could be an adaptive response to specific environments.When making inferences, people are often confronted with incomplete information. Looking for a healthy meal at a restaurant, for instance, we often do not have much detail about the entrées on the menu (e.g., the amount of cholesterol, fat, or preservatives in the dishes, or the cooking methods used) to help us infer which dish would be the wisest choice. Nevertheless, even with incomplete information, people infer which is the healthier option and make their choices. In the present article, the question addressed is how people should make inferences despite incomplete information.The question of how people deal with incomplete information has attracted increasing interest (see Ganzach