Infectivity of Cryptosporidium parvum isolated from asymptomatic adult goats to mice and goat kids

Noordeen, F.; Horadagoda, N. U.; Faizal, A.C.M.; Rajapakse, R. P. V. J.; Mariatulqabtiah, Abdul Razak; Arulkanthan, A.

doi:10.1016/s0304-4017(01)00578-7

Cited by 22 publications

(11 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Evidence from studies in other livestock species indicates a marked variation in the infectivity, shedding pattern, and virulence of Cryptosporidium isolates obtained from different sources. Cryptosporidium oocysts isolated from asymptomatic adult goats were infective to mice and goat kids (Noordeen et al 2002). The ability of oocysts from asymptomatic goats to produce infection in young goat kids and mice is likely to have a major impact on the epidemiology of the disease in susceptible livestock and man.…”

Section: Discussionmentioning

confidence: 99%

Molecular characterization of Cryptosporidium from animal sources in Qinghai province of China

et al. 2007

View full text Add to dashboard Cite

The presence of Cryptosporidium oocysts in 20 zoo animals of the Xining Zoo, 16 farm yaks and 42 farm goats in Qinghai province, China was investigated by an immunofluorescence test (IFT). The species and/or genotypes were determined by nested polymerase chain reaction (PCR) and sequence analysis of a fragment of the small subunit (SSU) rRNA gene. Cryptosporidium oocysts were found in 16 zoo animals, 2 yaks, and 15 goats by IFT. The IFT positive samples were further investigated by PCR, and 16 of them were found to be positive by that method also. Sequence analysis of the PCR products derived from Cryptosporidium oocysts from Black leopard (Panthera pardus), Heijing He (Grus nigricollis), Barbary sheep (Ammotragus lervia), Takin (Budorcas taxicolor), Lesser panda (Ailurus fulgens), and White-eared pheasant (Crossoptilon crossoptilon) fecal samples matched that of Cryptosporidium parvum mouse genotype. Sequence analyses of other PCR products were consistent with cervine genotype Cryptosporidium from Ibex (Capra ibex), a novel Cryptosporidium genotype from a wild yak (Bos mutus), C. bovis-like genotype from one goat sample and also a novel Cryptosporidium genotype from one other separate goat sample. The present work reports the first data on Cryptosporidium infections in animals from the Qinghai province of mountainous central western China and the first findings of the 'cervine' genotype in Capra ibex, C. bovis-like genotype and the new Cryptosporidium spp. in farm goat and in wild yak.

show abstract

Section: Discussionmentioning

confidence: 99%

Molecular characterization of Cryptosporidium from animal sources in Qinghai province of China

et al. 2007

View full text Add to dashboard Cite

show abstract

“…Cryptosporidium parvum is frequently associated with infections in neonate calves [74], while C. andersoni is more commonly associated with adult cows [75]. Chickens [76], hogs [77] sheep [77], goats [78], horses [77] and farmed elk [79] have also been shown to harbour Cryptosporidium infections and therefore represent possible agricultural sources of transmission for zoonotic disease. Pets such as dogs, cats, birds, snakes, lizards and ferrets can also be infected with Cryptosporidium parasites [22].…”

Section: Environmental Sources Of Cryptosporidiummentioning

confidence: 99%

Re-assessing the public health risk associated with the waterborne transmission of Cryptosporidium spp.

Ruecker

Neumann

2006

Reviews in Medical Microbiology

View full text Add to dashboard Cite

Cryptosporidium is a faecally transmitted parasite and an aetiologic agent of human enteric disease worldwide. Contaminated food, water, and direct contact with infected animals have long been considered risk factors for parasitic infection. The applications of molecular diagnostic tools in clinical and environmental research settings have inspired a new understanding of Cryptosporidium taxonomy and disease transmission. Once thought to be a non-specific parasite with a broad host range, cryptosporidia are now considered to be relatively host specific, bringing into question the true zoonotic potential of this parasite. Contaminated water is considered a major risk factor contributing to outbreaks of human cryptosporidiosis. In light of Cryptosporidium hostspecificity and the expanding complexity associated with the molecular epidemiology of this parasite, the ability to differentiate the various species and genotypes of Cryptosporidium from environmental water samples becomes imperative. These emerging concepts need to be integrated into the risk assessment strategies used to associate the public health impact of water supplies contaminated with Cryptosporidium spp.

show abstract

“…depende principalmente da carga parasitária, da idade e estado imunológico do hospedeiro (Silva et al 1999, Noordeen et al 2002, Bomfim et al 2005, Pavlovic et al 2010, sendo mais severa em jovens e imunossuprimidos (Vieira et al 1997, De Graff et al 1999. A manifestação clínica pode variar de assintomática a grave, que ocasionalmente culmina em óbito.…”

Section: Introductionunclassified

“…A manifestação clínica pode variar de assintomática a grave, que ocasionalmente culmina em óbito. A sintomatologia mais comum é a diarreia e coincide com o período de maior eliminação dos oocistos (Noordeen et al 2002).…”

Section: Introductionunclassified

“…Os adultos normalmente não apresentam sintomatologia e podem eliminar oocistos, servindo como reservatório para cabritos (Noordeen et al 2000, Noordeen et al 2002, Santín 2013. A principal via de transmissão é a oral, por meio da ingestão dos oocistos esporulados ou lambedura de material contaminado com estas estruturas parasitárias (Paraud & Chartier 2012).…”

Section: Introductionunclassified

See 1 more Smart Citation

Ocorrência da infecção por Cryptosporidium spp. em cabritos (Capra hircus)

et al. 2014

View full text Add to dashboard Cite

Pesq. Vet. Bras. 34(8):728-732, agosto 2014 728 RESUMO.-O presente estudo teve como objetivo determinar a ocorrência da infecção por Cryptosporidium spp. em cabritos de Quixadá, Ceará, Brasil. Participaram do estudo 400 cabritos, com idade entre três e 360 dias, de ambos os sexos, com e sem padrão racial definido, procedentes de 25 estabelecimentos rurais distribuídos em três circuitos. As fezes foram cadastradas de acordo com o aspecto e cor, distribuídas em tubos tipo "eppendorf ®" e congeladas in natura a -20°C, até o momento das extrações de DNA genô-mico do parasito com auxílio de kit comercial. Para amplificação de fragmentos da subunidade 18S do RNA ribossô-mico (rRNA) foi utilizada a "Nested"-PCR. A ocorrência de Cryptosporidium spp em cabritos de Quixadá foi de 7,50% (30/400). A frequência no período seco e no chuvoso foi de 9,55% (19/199) e 5,47% (11/201), respectivamente (χ 2 =2,39 e P>0,05). Amostras positivas foram identificadas em 64,00% (16/25) das propriedades estudadas e dessas amostras 50,00% (15/30) e 70,00% (21/30) tinham as fezes com aspecto e cor normais, respectivamente, sugerindo que cabritos assintomáticos estão eliminando oocistos. Não foi observada positividade para Cryptosporidium spp.

show abstract

Infectivity of Cryptosporidium parvum isolated from asymptomatic adult goats to mice and goat kids

Cited by 22 publications

References 15 publications

Molecular characterization of Cryptosporidium from animal sources in Qinghai province of China

Molecular characterization of Cryptosporidium from animal sources in Qinghai province of China

Re-assessing the public health risk associated with the waterborne transmission of Cryptosporidium spp.

Ocorrência da infecção por Cryptosporidium spp. em cabritos (Capra hircus)

Contact Info

Product

Resources

About