Infective Ear Disease in Factory Employees

Johnston, Colin M.

doi:10.1136/bmj.2.4589.1049

Cited by 16 publications

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“…Schuknecht [11] described the focal or diVuse replacement of the dermis of the tympanic membrane and adjacent canal wall with granulation tissue as a characteristic of GM. Because of the incidence of this minor illness is low [4, [12][13][14][15], GM is poorly understood and has received little attention in the medical Weld. Moreover, it is diYcult to establish a standard treatment protocol since the clinical features of GM, including diagnosis and treatment, are controversial.…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics of granular myringitis treated with castellani solution

Kim

2011

Eur Arch Otorhinolaryngol

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Aim of the study is to observe clinical manifestations of granular myringitis (GM) treated with castellani solution. Twenty-four patients (18 women and 6 men; mean age, 49.7 years; range, 9-77 years) diagnosed with GM and treated with castellani solution were enrolled retrospectively. Topical treatment using castellani solution with or without curettage of a granular lesion and serial otoendoscopy-aided photographic documentation of the tympanic membrane were performed. Outpatient follow-up period ranged from 3 to 72 months and the mean follow-up period was 14.4 months. GM was classified into marginal/non-marginal type and ulcerative/polypoid subtype using a new scale. According to the scale used in this study, the marginal and ulcerative GM was the predominant type of GM lesion. Bacterial cultures of ear discharges from 19 patients revealed Staphylococcus, Corynebacterium and Providencia stuartii in 12, 5, and 1 patient, respectively and no growth of bacteria in one patient. Of 24 patients, 23 showed complete resolution of GM after treatment with castellani solution. However, one patient had a persistent, small, dry, deepithelialized lesion and eight others required more than 3 months for complete recovery owing to a persistent residual lesion. There was recurrence in two patients but the lesion resolved after additional castellani treatment. Topical application of castellani solution is a simple and effective treatment for GM. This study suggests a potential of castellani solution for treatment of GM with a serial photographic documentation and novel classification scale for description of lesions. A sufficiently long follow-up period is essential to confirm a complete recovery of GM.

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Section: Discussionmentioning

confidence: 99%

Clinical characteristics of granular myringitis treated with castellani solution

Kim

2011

Eur Arch Otorhinolaryngol

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“…During and after the recent war otologists were impressed by the excellent results they could obtain when treatment was carried out regularly and personally (Banham, 1944;Scott Stevenson and Ballantyne, 1945;Johnston, 1948).…”

Section: Pathology Of Chronic Suppurative Otifis Mediamentioning

confidence: 99%

“…Spirit drops and wicks also give good results provided the cleansing is thorough and the medicament is brought into contact with the infected parts. Treatment is often needed daily, rarely less frequently than twice a week, and may take anything from a week to seven months to produce a dry ear (Johnston, 1948). It is timeconsuming, requires trained personnel, and in civilian practice is often impossible to carry out adequately.…”

Section: Pathology Of Chronic Suppurative Otifis Mediamentioning

confidence: 99%

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confidence: 99%

“…Otorrhoea formed the bulk of the cases. Johnston (1948) found that of 1,902 factory employees 3.3 % had suppurating middle ears, and Asherson (1950) states that 1 % of the school population of London in 1932 were treated for chronic otorrhoea. These figures apply to special sections of the population, but most otologists would agree that otorrhoea is equally common in many other groups as well.…”

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Treatment of Chronic Otorrhoea with Chloramphenicol

Lewis¹,

Gray²

1951

BMJ

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The common causes of persistent ear discharge are chronic otitis media, chronic otitis externa, and infection in the cavities made by tympano-mastoidectomies and fenestration operations. It is difficult to assess the proportion of the population suffering from running ears, but Formby (1942) reported that just over 2% of recruits examined during the 1939-45 war were rejected because of chronic ear diseases. Otorrhoea formed the bulk of the cases. Johnston (1948) found that of 1,902 factory employees 3.3 % had suppurating middle ears, and Asherson (1950) states that 1 % of the school population of London in 1932 were treated for chronic otorrhoea.

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The clinical features and pathogenesis of myringitis granulosa

Makino

Amatsu

Kinishi

et al. 1988

Arch Otorhinolaryngol

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Myringitis granulosa is not a rare pathologic condition of the tympanic membrane. However, the condition can be misdiagnosed as chronic suppurative otitis media, since intermittent purulent discharge is the commonest symptom in both disorders. Although the clinical features of myringitis granulosa have been well described by several authors, its pathogenesis is still obscure. In this study, 40 cases of myringitis granulosa were examined in detail to clarify the clinical features and the pathogenesis present. No drum perforations, no hearing impairments and normal X-ray findings indicated that myringitis granulosa had no relation to chronic suppurative otitis media. The other areas of the affected tympanic membrane, except for the site of granulation, showed such pathologic conditions as atrophy, clouding and calcifications. In these pathologic tympanic membranes, epithelial migration was disturbed to a high degree. We suggest that the granulation process on the tympanic membrane should be divided into two stages: (1) injury reaching the lamina propria of the tympanic membrane; and (2) disturbed epithelization of the tympanic membrane. The disturbance of epithelial migration of the tympanic membrane occurs with both stages.

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Infective Ear Disease in Factory Employees

Cited by 16 publications

References 0 publications

Clinical characteristics of granular myringitis treated with castellani solution

Clinical characteristics of granular myringitis treated with castellani solution

Treatment of Chronic Otorrhoea with Chloramphenicol

The clinical features and pathogenesis of myringitis granulosa

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