Infectious mononucleosis with acute thrombocytopenia

Flanagan, N. G.; Rowlands, Alison; Sloan, M.E.; Ridway, J C

doi:10.1016/s0163-4453(89)94928-1

Cited by 4 publications

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In all these patients thrombocytopenia was benign and self-limiting, requiring no interventions [3]. There are a few reports of thrombocytopenia requiring treatment with steroids [4][5][6][7][8][9] or intravenous immunoglobulin [6,10]; in one report acyclovir was given [6]. By contrast, IM causing thrombocytopenia that is associated with life threatening bleeding is rare.…”

Section: Discussionmentioning

confidence: 99%

“…Infectious mononucleosis (IM) mostly presents as acute onset fever, sore throat and hepatosplenomegaly [1]. Platelet count may be reduced in this illness transiently but is rarely severe enough to result in lifethreatening bleeding [2][3][4][5][6]. Herein, we describe a child who presented with high grade fever and life threatening bleeding from multiple sites causing diagnostic confusion with more common clinical picture of acute leukemia.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Infectious mononucleosis due to Epstein Barr virus infection presenting as life threatening thrombocytopenic bleeding

Nandi

Das

2015

J Pediatr Infect Dis

View full text Add to dashboard Cite

Acute onset transient thrombocytopenia is a known complication of infectious mononucleosis due to Epstein Barr virus infection. Infectious mononucleosis presenting with severe thrombocytopenia resulting in life threatening bleeding is rare, and may cause diagnostic confusion with more sinister conditions like acute leukemia. We report one such case of severe bleeding in association with Epstein Barr virus infection in a previously healthy adolescent girl and discuss the possible mechanisms of thrombocytopenia in infectious mononucleosis.

show abstract