Infectious complications associated with ventricular assist devices

Abstract

Improvements in technology, patient selection, and patient management have led to a wider clinical application of mechanical circulatory support. Critically ill patients often develop multiorgan ischemia and are prone to multiple complications. Despite these advances, infection is a common and sometimes lethal complication of support with ventricular assist devices. This article provides guidelines for the prevention and management of infection in patients who require such support.

An Overview of Approved and Investigational Left Ventricular Assist Devices

“…Cardiopulmonary bypass and blood-pump rheology also cause platelet dysfunction. Infection rates are about 30% to 40% and contribute to significant morbidity (15). Infection usually occurs because the driveline acts as a conduit from the outside environment; moreover, the large surgical pocket created to house the LVAD can collect undrained blood and serve as a potential culture medium.…”