Infections of Joints, Synovium-Lined Structures, and Soft Tissue

Demicco, Elizabeth G.; Kattapuram, Susan V.; Kradin, Richard L.; Rosenberg, Andrew E.

doi:10.1016/b978-0-323-44585-6.00015-1

Cited by 3 publications

(1 citation statement)

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“…Histopathology may show villonodular synovitis, pannus and sinus tract formation, non-necrotizing granulomas, and spherules containing endospores. It is a septic arthritis demonstrating synovial proliferation rather than synovial fluid accumulation[ 30 ]. The main antifungal drugs are oral azoles (fluconazole and itraconazole), which have largely replaced the role of Amp B, except in immunocompromised patients and disseminated coccidioidomycosis[ 31 ].…”

Section: Common Pathogensmentioning

confidence: 99%

Fungal arthritis: A challenging clinical entity

Mishra¹,

Juneja²

2023

World J Orthop

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There has been an increasing incidence of fungal infections in recent years. Rarely joints are also affected by fungal infections. Mainly, these infections develop in prosthetic joints, but sometimes native joints are also involved. Candida infections are mostly reported, but patients may also develop infections secondary to non- Candida fungi, especially Aspergillus . Diagnosis and management of these infections is challenging and may involve multiple surgical interventions and prolonged antifungal therapy. Despite this, these infections are associated with high morbidity and mortality. This review described the clinical features, risk factors, and therapeutic interventions required to manage fungal arthritis.

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Section: Common Pathogensmentioning

confidence: 99%