Infection Control Programs and Antibiotic Control Programs to Limit Transmission of Multi-Drug Resistant Acinetobacter baumannii Infections: Evolution of Old Problems and New Challenges for Institutes

Abstract

Background: Acinetobacter baumannii complex (A. baumannii) has been isolated worldwide. The rapid spread of multidrug-resistant A. baumannii complex (MDRAB) in clinical settings has made choosing an appropriate antibiotic to treat these infections and executing contact precautions difficult for clinicians. Although controlling the transmission of MDRAB is a high priority for institutions, there is little information about MDRAB control. Therefore, this study evaluated infection control measures for A. baumannii infections, clusters and outbreaks in the literature. Methods: We performed a review of OVID Medline (from 1980 to 2015), and analyzed the literature. Results: We propose that both infection control programs and antibiotic control programs are essential for control of MDRAB. The first, effective control of MDRAB infections, requires compliance with a series of infection control methods including strict environmental cleaning, effective sterilization of reusable medical equipment, concentration on proper hand hygiene practices, and use of contact precautions, together with appropriate administrative guidance. The second strategy, effective antibiotic control programs to decrease A. baumannii, is also of paramount importance. Conclusion: We believe that both infection control programs and antibiotics stewardship programs are essential for control of MDRAB infections.

Evaluation of the ability of Acinetobacter baumannii to form biofilms on six different biomedical relevant surfaces

“…Acinetobacter baumannii can disseminate and persist in hospital environments, causing nosocomial outbreaks and serious disease in the critically ill (Towner ; Chen et al . ; Weber et al . ).…”

Determination of Different Fluoroquinolone Mechanisms Among Clinical Isolates of Acinetobacter baumannii in Tehran, Iran

“…(1)(2)(3)(4). Bacteremia is caused by toxic shock in 25% to 30% of the cases and usually occurs due to disseminated intravascular coagulation.…”

Antimicrobial Stewardship Program at a tertiary teaching hospital in Vietnam: A longitudinal observational study

“…These represent the most common pathogens in tertiary hospitals in Vietnam. Experience shows the prevention of an increased burden of hospital acquired infection by these pathogens can be achieved economically through contact precaution, hand hygiene, use of personal protective equipment, and medical equipment disinfection, coupled with appropriate antibiotic usage to counter emerging resistance [8].…”