Background: Around 7 million patients undergo percutaneous interventional vascular procedures worldwide annually and this number is expected to escalate further in coming years. The aim of this study was to analyse immediate and short term follow up of patients with acute coronary syndrome (ACS) who had undergone percutaneous coronary intervention (PCI) through femoral route and closure with vascular closure device. Methods: This was non randomised, single centre study and was conducted in a tertiary care institution between January 2013 to June 2014 with 62 ACS patients undergoing femoral access invasive cardiac interventional procedure. Perclose A-T system was used in all patients as closure device. Patients were followed up to 15 days of clinical evaluation. Results: Of 62 ACS patients, 40 (64.5%) were with non-ST elevation myocardial infarction and 22 (35.5%) patients had history of unstable angina. The perclose device achieved closure within 5 to 10 minutes and all patients were kept in hospital stay for 2 to 3 days. There was one major complication of continuous bleeding, one incidence of small pseudo aneurysm, and two incidences of small hematomas with need of blood transfusion. Conclusions: This study demonstrates the ability of arterial closure device to safely and effectively achieve arterial closure in patients undergoing percutaneous intervention for ACS. Manzil AS et al. Int J Res Med Sci. 2017 Mar;5(3):778-781 International have improved patient comfort, and shortened the time needed for hemostasis, ambulation and thereby discharge.
Keywords6 Several VCDs are available with different mode and method of closure (intravascular or extravascular), time of hemostasis, time of ambulation and type of healing (primary or secondary). 7 But there was paucity of data to support use of arterial closure devices in patients with ACS. Therefore, we analysed immediate and short term follow up of patients with ACS who had undergone PCI through femoral route and closure with vascular closure device.
METHODSThis was non randomised, single centre study and was conducted in a tertiary care institution between January 2013 to June 2014 with 62 ACS patients undergoing femoral access invasive cardiac interventional procedure. Patients were selected between the ages of 18 and 75 years who were scheduled emergency coronary interventional procedures. The target vessel lumen diameter was at least 6 mm and 7 Fr arterial sheaths were utilised.Patients were excluded if they had a body mass index (BMI) of <20 or >40, previous femoral arterial access within 3 months, any bleeding diathesis or anaemia. ST elevation myocardial infarction (STEMI), Cardiogenic shock, hemodynamic unstable patients were excluded. All patients underwent iliac and femoral angiogram prior to closure. Outcomes evaluated include time to hemostasis, time to ambulation, rates of vascular complications. Vascular complications that were evaluated include major complications including vascular injury requiring surgical repair, need for blood transfusio...