Infection after primary anatomic versus primary reverse total shoulder arthroplasty

Florschütz, Anthony V.; Lane, Paul D.; Crosby, Lynn A.

doi:10.1016/j.jse.2014.12.036

Cited by 78 publications

(43 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is an infection rate of 0.7% to 3.29% following conventional total shoulder replacement; 41,46,59,60 0.5% to 2.7% following shoulder hemiarthroplasty; 41,45,59,78 and up to 5% following reverse shoulder arthroplasty. 12,41,60,97 Florschutz et al, 60 Smucny et al 94 and Richards et al 41 all reported higher infection rates in patients undergoing reverse shoulder arthroplasty compared to anatomic total shoulder arthroplasty. Revision shoulder arthroplasty had a much higher risk of infection with rates of 7% 55 to 32%.…”

Section: Incidence Of Psimentioning

confidence: 99%

Scoping review: Diagnosis and management of periprosthetic joint infection in shoulder arthroplasty

et al. 2018

View full text Add to dashboard Cite

Background: The aim of this scoping review is to assess the current evidence regarding periprosthetic shoulder infection to inform development of evidence and consensus-based guidelines. Methods: A search of Medline, Embase and PubMed was performed; two authors screened the results independently for inclusion. Results: Totally 88 studies were included. Incidence of periprosthetic shoulder infection ranged from 0.7% to 7%. The most common organisms to cause periprosthetic shoulder infection were Propionibacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis and coagulase-negative Staphylococcus. Male gender and younger age are the most reported risk factors. Erythrocyte sedimentation rate, C-reactive protein and serum/synovial biomarkers had limited diagnostic accuracy. Thirty-nine studies reported the outcome of surgical management of periprosthetic shoulder infection. Eradication rates vary from 54% to 100% for debridement procedures; 66-100% for permanent spacers; 50-100% following single-stage revision; 60-100% following two-stage revision; and 66-100% following resection arthroplasty. Conclusion: There is wide heterogeneity in study designs and outcomes of studies are often contradictory and due to issues with methodology and small sample sizes the optimal pathways for diagnosis and management cannot be determined from this review. Future research should be based on larger cohorts and randomised trials where feasible to provide more valid research for guiding future treatment of periprosthetic shoulder infection.

show abstract

Section: Incidence Of Psimentioning

confidence: 99%

Scoping review: Diagnosis and management of periprosthetic joint infection in shoulder arthroplasty

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Whereas C acnes and S epidermidis are frequently noted contaminants and infectious agents in the literature, E Coli is not. 1,2,9,33,34 One prior study using NGS in revision shoulder arthroplasty cases identified E coli in 2 of the 44 (5%) revision cases. 24 Yet, NGS in our study identified a surprisingly high presence of E Coli in 20% (5/25) of the skin samples and in 16% (4/25) of the deep tissue samples.…”

Section: Discussionmentioning

confidence: 99%

Next-generation sequencing for diagnosis of infection: is more sensitive really better?

Rao

MacLean

Naylor

et al. 2020

Journal of Shoulder and Elbow Surgery

View full text Add to dashboard Cite

“…The novel role of these bacteria is partly driven by advances in the medical field, including the now common use of joint prostheses and catheters; commonly being contaminated by the skin microbiota, including Staphylococcus epidermidis and C . acnes [ 12 ], showing a localization-triggered bacterial pathogenesis [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Platelet activation and aggregation by the opportunistic pathogen Cutibacterium (Propionibacterium) acnes

Petersson¹,

Kilsgård²,

Shannon³

et al. 2018

PLoS ONE

View full text Add to dashboard Cite

Cutibacterium (Propionibacterium) acnes, considered a part of the skin microbiota, is one of the most commonly isolated anaerobic bacteria from medical implants in contact with plasma. However, the precise interaction of C. acnes with blood cells and plasma proteins has not been fully elucidated. Herein, we have investigated the molecular interaction of C. acnes with platelets and plasma proteins. We report that the ability of C. acnes to aggregate platelets is dependent on phylotype, with a significantly lower ability amongst type IB isolates, and the interaction of specific donor-dependent plasma proteins (or concentrations thereof) with C. acnes. Pretreatment of C. acnes with plasma reduces the lag time before aggregation demonstrating that pre-deposition of plasma proteins on C. acnes is an important step in platelet aggregation. Using mass spectrometry we identified several plasma proteins deposited on C. acnes, including IgG, fibrinogen and complement factors. Inhibition of IgG, fibrinogen or complement decreased C. acnes-mediated platelet aggregation, demonstrating the importance of these plasma proteins for aggregation. The interaction of C. acnes and platelets was visualized using fluorescence microscopy, verifying the presence of IgG and fibrinogen as components of the aggregates, and co-localization of C. acnes and platelets in the aggregates. Here, we have demonstrated the ability of C. acnes to activate and aggregate platelets in a bacterium and donor-specific fashion, as well as added mechanistic insights into this interaction.

show abstract

Infection after primary anatomic versus primary reverse total shoulder arthroplasty

Cited by 78 publications

References 21 publications

Scoping review: Diagnosis and management of periprosthetic joint infection in shoulder arthroplasty

Scoping review: Diagnosis and management of periprosthetic joint infection in shoulder arthroplasty

Next-generation sequencing for diagnosis of infection: is more sensitive really better?

Platelet activation and aggregation by the opportunistic pathogen Cutibacterium (Propionibacterium) acnes

Contact Info

Product

Resources

About