Infection à Helicobacter pylori chez l’enfant de 6 mois à 16 ans à Brazzaville (Congo)

Molecular Detection of Helicobacter pylori and its Antimicrobial Resistance in Brazzaville, Congo

“…It confirms an early report concerning children from the same city [18] and is in line with other studies from Western Africa: Ghana [19], and Senegal [20], and Eastern Africa: Kenya [21], as well as the general knowledge on epidemiology of the infection. It confirms an early report concerning children from the same city [18] and is in line with other studies from Western Africa: Ghana [19], and Senegal [20], and Eastern Africa: Kenya [21], as well as the general knowledge on epidemiology of the infection.…”

“…As expected, H. pylori prevalence in Brazzaville, Congo, is quite high (89%), acquired early in childhood, as there is no statistically significant difference between the age groups. It confirms an early report concerning children from the same city [18] and is in line with other studies from Western Africa: Ghana [19], and Senegal [20], and Eastern Africa: Kenya [21], as well as the general knowledge on epidemiology of the infection. But the main interest of this study is to bring us important information on the status of H. pylori resistance against the antibiotics used in treating this infection.…”

<i>cagA</i> and <i>vacA</i> <i>Helicobacter pylori</i> Pathogenicity Factors in Brazzaville, Congo

“…The results of this study can explain the frequency of gastritis, PUD and gastric cancers in Brazzaville, Congo. Indeed, Ibara et al reported 62.02% gastritis (first cause of gastric pathologies), 11.29% PUD and 3.60% gastric adenocarcinomas, despite the fact that a causal relationship with H. pylori has not been es-tablished [42]. H. pylori infection and gastric carcinogenesis processes in Congo must be fought using strategies based on the recommendation for H. pylori diagnosis and antimicrobial susceptibility testing in order to eradicate H. pylori and prevent gastritis, PUD and carcinoma.…”

Recurrent Iron Deficiency Anemia Revealing Chronic Gastritis with <i>Helicobacter pylori</i>

“…Among the possible causes, the role of H. pylori infection remains controversial [2] [3]. In Congo, the prevalence of H. pylori infection is estimated at 47.8% in children [4] and 89% in 2014 in the general population [5]. The main causes of iron deficiency anemia are dominated by parasitosis and malnutrition [4].…”