Infecciones invasivas por Streptococcus pneumoniae: Estudio epidemiológico e importancia del desarrollo de un sistema de vigilancia

Lactobacillus casei administration reduces lung injuries in a Streptococcus pneumoniae infection in mice

“…There is growing evidence that certain aspects of the immune response greatly contribute to the high mortality rate: while immunosuppressed patients die as a consequence of poor host response, immunocompetent hosts face overwhelming inflammatory reactions that may lead to tissue injury, shock and, eventually, death [2,3]. Pneumonia is the most common clinical presentation of pneumococcal disease; in fact, 95% of cases appear as pneumonia or meningitis and S. pneumoniae continues to cause considerable morbidity and mortality throughout the world [4]. Consequently, it is necessary to develop more effective methods for the prevention of pneumococcal infections, especially in developing countries, where the incidence is high [4].…”

Lactococcus lactisas an adjuvant and delivery vehicle of antigens against pneumococcal respiratory infections

“…An estimated 700,000 to one million children, most of whom live in developing countries, die of pneumococcal diseases every year. [2][3][4] In these countries, pneumococcal disease is common in children under two years of age, including newborn infants, while in the elderly population incidence rates as unknown. The most common form of the disease is bacteremic pneumococcal pneumonia, whose highest incidence is associated with both extremes of age (children <2 years of age and adults >65 years of age).…”

Inflammation–hemostasis relationship in infected malnourished mice: modulatory effect of Lactobacillus casei CRL 431

“…Malbrán'', Buenos Aires, Argentina. The pathogen strain belongs to serotype 14, one of the ten most frequent serotypes isolated in pneumococcal infections in Argentina [14].…”