Infarcts of the Liver

Woolling, Kenneth R.; Baggenstoss, Archie H.; Weir, James

doi:10.1016/s0016-5085(51)80059-3

Cited by 44 publications

(12 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The parenchyma is protected against ischemia by its double blood supply, and most individuals tolerate hepatic artery ligation without infarction 25. Large infarcts are usually associated with the obstruction of both the hepatic artery and the portal vein . Data from our present study show that when portal vein and hepatic artery ligation are performed at the same time, the ligated liver tissues undergo massive necrosis.…”

Section: Discussionmentioning

confidence: 51%

Liver regeneration after portal vein plus hepatic artery ligation performed heterochronously in rats

Kong

Kusano

Arase

et al. 2002

Journal of Hepato-Biliary-Pancreatic Surgery

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 51%

Liver regeneration after portal vein plus hepatic artery ligation performed heterochronously in rats

Kong

Kusano

Arase

et al. 2002

Journal of Hepato-Biliary-Pancreatic Surgery

View full text Add to dashboard Cite

show abstract

“…Hepatic infarction is an uncommon occurrence with an incidence in necropsy series ranging from none to 1 in 338 necropsies [1,2]. More recently Seeley et al [3] found 14 cases of hepatic infarction in a series of 700 consecutive necropsies suggesting that the incidence of this condition may be higher than that previously described or recognized.…”

Section: Discussionmentioning

confidence: 99%

“…Hepatic infarction occurring in the absence of vascular occlusion has been reported in those patients with underlying cardiovascular disease or disease of the gall bladder or biliary tract [2]. Hepatic infarcts have also been observed in those subjected to prolonged periods of shock.…”

Section: Discussionmentioning

confidence: 99%

Angiographic demonstration of non-occlusive hepatic infarction with scintigraphic and microscopic correlation

Sundaram

Srivisal

Lagos

et al. 1978

Gastrointest Radiol

View full text Add to dashboard Cite

The angiographic appearances of histologically proven hepatic infarction without vascular occlusion has not, to our knowledge, been previously described. A case of non-occlusive hepatic infarction in a diabetic patient is presented and correlated with scintigraphic and microscopic findings. It would appear to be the first recorded case of hepatic infarction associated with diabetic ketoacidosis. A follow-up angiogram showed resolution. The literature is briefly reviewed.

show abstract

“…In addition it has been suggested in a retrospective study (Woolling, Baggenstoss, and Weir, 1951) that portal vein occlusion combined with a general circulatory disturbance may cause infarction but there has been no general support for this theory.…”

Section: Discussionmentioning

confidence: 99%

Zahn's `infarcts' of the liver

Horrocks

Tapp

1966

Journal of Clinical Pathology

View full text Add to dashboard Cite

SYNOPSIS Three patients were found at necropsy to have Zahn's 'infarcts' of the liver. In one of these cases the 'infarct' merely showed severe centrilobular congestion. In the other two cases there was centrilobular necrosis, and in one of these early fibrosis was seen. Portal vein occlusion was present in all three cases and this had followed splenectomy in two of them. Necropsy was performed six hours after death. There was an early mediastinitis and bronchopneumonic consolidation of the right lower lobe. Other significant findings were confined to the liver and portal venous system. Externally the liver was generally pale but showed several large, dark red, sharply defined areas. On section these had the typical 'nutmeg' appearance normally associated with chronic venous congestion. In such areas, many large intrahepatic branches of the portal vein were occluded by thrombus. The splenic vein was also filled by thrombus which extended from the ligated splenic pedicle to the origin of the portal vein. No obstruction of the extrahepatic part of the portal vein was present and there was no abnormality of the hepatic artery or veins.Microscopy ofliver The pale areas in the liver showed considerable fatty change. In the dark red areas there was Received for publication 22 March 1966 generalized congestion of the sinusoids, most prominent in the centrilobular zones (Fig. 1). Liver parenchymal cells in the congested areas were shrunken and contained small amounts of lipofuscin pigment (Fig. 2). Several branches of the portal vein were occluded by organizing thrombus. The portal tracts were otherwise normal.CASE 2 A 70-year-old woman was seen during the following month complaining of constant epigastric pain of three weeks' duration. She was found to have an epigastric mass and a barium meal demonstrated a gastric carcinoma. A total gastric resection with oesophago-jejunostomy and splenectomy was carried out. Progress thereafter was at first good but 18 hours before death she became hypotensive and had signs suggesting peritonitis. She died on the sixth post-operative day.At necropsy 36 hours after death localized peritonitis due to failure of the anastomosis was present. There was haemorrhage into the left adrenal gland. The remaining abnormalities were limited to the liver and portal venous system. The liver showed lesions similar to those described in case 1, but on section there was also thrombus in the larger branches of the portal vein supplying these areas. The splenic vein was filled by thrombus to its junction with the superior mesenteric vein. No lesions were found in the hepatic artery or veins.

show abstract

Infarcts of the Liver

Cited by 44 publications

References 1 publication

Liver regeneration after portal vein plus hepatic artery ligation performed heterochronously in rats

Liver regeneration after portal vein plus hepatic artery ligation performed heterochronously in rats

Angiographic demonstration of non-occlusive hepatic infarction with scintigraphic and microscopic correlation

Zahn's `infarcts' of the liver

Contact Info

Product

Resources

About