Induction to delivery interval using transcervical Foley catheter plus oxytocin and vaginal misoprostol: A comparative study at Aminu Kano Teaching Hospital, Kano, Nigeria

Garba, Ibrahim; Muhammed, Abubakar Shehu; Muhammad, Zakari; Galadanci, Hadiza; Rabiu, Ayyuba; Abubakar, IS

doi:10.4103/1596-3519.188890

Cited by 9 publications

(20 citation statements)

References 19 publications

(15 reference statements)

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“…Of the 103 trials identified, just 63 were RCTs. 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 The majority of RCTs were single-center trials conducted in academic hospitals, which can limit the generalizability of the results to other community-based populations. Among the 12 multicenter trials, the number of centers ranged from 2 to 49 and tended to include both university-affiliated and community hospitals.…”

Section: Limitations Of Trials On Labor Inductionmentioning

confidence: 99%

“…For example, two trials compared the Foley catheter plus oxytocin versus vaginal misoprostol. 28 70 Another compared vaginal dinoprostone with or without sequential oxytocin versus vaginal misoprostol plus sequential oxytocin. 83 These trials may have yielded more meaningful data if the combination agents were compared with the same single agents (e.g., Foley's catheter plus oxytocin vs. Foley's catheter alone or oxytocin alone).…”

Section: Limitations Of Trials On Labor Inductionmentioning

confidence: 99%

“…The international trials assessed a wider variety of combination methods, with the majority evaluating mechanical methods plus oxytocin or misoprostol: the Foley catheter plus oxytocin versus vaginal misoprostol ( n = 2), 28 70 the Foley catheter plus vaginal misoprostol versus vaginal misoprostol or the Foley catheter alone ( n = 3), 26 41 53 and double-balloon catheter plus oral misoprostol versus oral misoprostol alone ( n = 2). 35 65 A few of the international trials assessed combinations of pharmacological methods, including the dinoprostone vaginal insert plus concurrent oxytocin versus sequential use of the dinoprostone insert and oxytocin ( n = 1), 63 the dinoprostone vaginal insert with or without sequential oxytocin versus vaginal misoprostol plus sequential oxytocin ( n = 1), 83 and vaginal misoprostol plus sequential oxytocin versus oxytocin alone ( n = 2).…”

Section: Limitations Of Trials On Labor Inductionmentioning

confidence: 99%

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Challenges and Limitations of Clinical Trials on Labor Induction: A Review of the Literature

Viteri

Sibai

2018

AJP Rep

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Induction of labor is a common obstetric procedure performed in nearly a quarter of all deliveries in the United States. Pharmacological (prostaglandins, oxytocin) and/or mechanical methods (balloon catheters) are commonly used for labor induction; however, there is ongoing debate as to which method is the safest and most effective. This narrative review discusses key limitations of published trials on labor induction, including the lack of well-designed randomized controlled trials directly comparing specific methods of induction, heterogeneous trial populations, and wide variation in the protocols used and outcomes reported. Furthermore, the majority of published trials were underpowered to detect significant differences in the most clinically relevant efficacy and safety outcomes (e.g., cesarean delivery, neonatal mortality). By identifying the limitations of labor induction trials, we hope to highlight the importance of quality published data to better inform guidelines and drive evidence-based treatment decisions.

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Section: Limitations Of Trials On Labor Inductionmentioning

confidence: 99%

Section: Limitations Of Trials On Labor Inductionmentioning

confidence: 99%

Section: Limitations Of Trials On Labor Inductionmentioning

confidence: 99%

See 1 more Smart Citation

Challenges and Limitations of Clinical Trials on Labor Induction: A Review of the Literature

Viteri

Sibai

2018

AJP Rep

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“…The characteristics of the studies included in the meta-analysis are shown in table 1. From the four included studies three were conducted in the USA, (13,(18)(19), one in Nigeria (20). In general, the included participants had singleton pregnancies with an unfavorable cervix, intact membranes, and with the fetus in cephalic presentation in the third trimester of pregnancy.…”

Section: Characteristics Of Studiesmentioning

confidence: 99%

“…Three studies recruited primi-and multigravida women (13,(18)(19). One study enrolled only multigravida women (20) and one enrolled only primigravida women (18). Only in two studies the main outcomes were reported separately by primi and multigravidas (13,19).…”

Section: Characteristics Of Studiesmentioning

confidence: 99%

Concurrent administration of oxytocin with Foley catheter versus misoprostol for induction of labor: A systematic review

Maa¹,

S²,

Abedi³

et al. 2020

Preprint

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Objectives: Around one- third of pregnancies require labor induction due to issues such as post-term pregnancy, stillbirth, and medical complications. This systematic review aimed to evaluate the effect of concurrent administration of Foley catheter plus oxytocin vs. misoprostol on labor induction. Methods: The search was conducted in April 2019. The following databases were searched: PubMed, SCOPUS, Cochrane Central Register of controlled trials and Web of Science. Primary outcomes included mode of delivery and cesarean section rate. Secondary outcomes were the mean time of induction to delivery and delivery in less than 12 hours from induction. Data were analyzed using RevMan. For binary outcomes, the odds ratio with 95% confidence intervals (CI), and for continuous outcomes, the mean difference (MD) with 95% CI was measured. Results: Four studies were included in this review. The cesarean section and vaginal delivery rate in Foley + oxytocin was not significantly different from misoprostol (OR = 0.95; 95 % CI: 0.70, 1.30) and (OR = 0.92; 95 % CI: 0.66, 1.29) respectively. Foley + oxytocin decreased the mean time of induction to delivery compared to misoprostol (MD = 0.60; 95 % CI: 0.03, 1.16), and increased delivery in less than 12 hours from induction (OR = 2.08; 95 % CI: 1.43, 3.02). Conclusion: Although the rate of cesarean and vaginal delivery was not significant in two groups of Foley catheter + oxytocin and misoprostol, the mean time of induction to delivery reduced and delivery in less than 12 hours from induction increased in the Foley +oxytocin.

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Mechanical methods for induction of labour

Vaan

Eikelder

Jozwiak

et al. 2019

Cochrane Database of Systematic Reviews

100

117

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BackgroundMechanical methods were the first methods developed to ripen the cervix and induce labour. During recent decades they have been substituted by pharmacological methods. Potential advantages of mechanical methods, compared with pharmacological methods may include reduction in side effects that could improve neonatal outcomes. This is an update of a review first published in 2001, last updated in 2012.ObjectivesTo determine the effectiveness and safety of mechanical methods for third trimester (> 24 weeks' gestation) induction of labour in comparison with prostaglandin E2 (PGE2) (vaginal and intracervical), low‐dose misoprostol (oral and vaginal), amniotomy or oxytocin.Search methodsFor this update, we searched Cochrane Pregnancy and Childbirth’s Trials Register, , the WHO International Clinical Trials Registry Platform (), and reference lists of retrieved studies (9 January 2018). We updated the search in March 2019 and added the search results to the awaiting classification section of the review.Selection criteriaClinical trials comparing mechanical methods used for third trimester cervical ripening or labour induction with pharmacological methods.Mechanical methods include: (1) the introduction of a catheter through the cervix into the extra‐amniotic space with balloon insufflation; (2) introduction of laminaria tents, or their synthetic equivalent (Dilapan), into the cervical canal; (3) use of a catheter to inject fluid into the extra‐amniotic space (EASI).This review includes the following comparisons: (1) specific mechanical methods (balloon catheter, laminaria tents or EASI) compared with prostaglandins (different types, different routes) or with oxytocin; (2) single balloon compared to a double balloon; (3) addition of prostaglandins or oxytocin to mechanical methods compared with prostaglandins or oxytocin alone.Data collection and analysisTwo review authors independently assessed trials for inclusion and assessed risk of bias. Two review authors independently extracted data and assessed the quality of the evidence using the GRADE approach.Main resultsThis review update includes a total of 113 trials (22,373 women) contributing data to 21 comparisons. Risk of bias of trials varied. Overall, the evidence was graded from very‐low to moderate quality. All evidence was downgraded for lack of blinding and, for many comparisons, the effect estimates were too imprecise to make a valid judgement.Balloon versus vaginal PGE2: there may be little or no difference in vaginal deliveries not achieved within 24 hours (average risk ratio (RR) 1.01, 95% confidence interval (CI) 0.82 to 1.26; 7 studies; 1685 women; I² = 79%; low‐quality evidence) and there probably is little or no difference in caesarean sections (RR 1.00, 95% CI 0.92 to 1.09; 28 studies; 6619 women; moderate‐quality evidence) between induction of labour with a balloon catheter and vaginal PGE2. A balloon catheter probably reduces the risk of uterine hyperstimulation with fetal heart rate (FHR) changes (RR 0.35, 95% CI 0.18 to 0.67; 6 studies; 1966 ...

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Induction to delivery interval using transcervical Foley catheter plus oxytocin and vaginal misoprostol: A comparative study at Aminu Kano Teaching Hospital, Kano, Nigeria

Cited by 9 publications

References 19 publications

Challenges and Limitations of Clinical Trials on Labor Induction: A Review of the Literature

Challenges and Limitations of Clinical Trials on Labor Induction: A Review of the Literature

Concurrent administration of oxytocin with Foley catheter versus misoprostol for induction of labor: A systematic review

Mechanical methods for induction of labour

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