Induction of chronic marginal periodontitis in an experimental sheep model: clinical, radiological and histological evaluation

Alexandru, Bogdan-Cătălin; Pharmacy, Cluj-Napoca; Popa, Marcel Sabin; Oană, Liviu; Georgiu, Carmen; Tăbăran, Flaviu; Macri, A.; Purdoiu, R. C.; Istrate, Dan; Dogaru, Gabriela; Lazăr, C; Bianca, Bosca; Peștean, Cosmin; Constantin, Anne-Marie; Sovrea, Alina

doi:10.25083/rbl/25.3/1511.1525

Cited by 2 publications

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“…The microscopic findings observed in sheep with periodontitis in this study were similar to those seen in previous studies and are mainly characterized by the presence of mononuclear inflammatory infiltrate, bone resorption and periodontal ligament destruction with varying degrees of severity (Orr et al 1979, Alexandru et al 2020. Varying degrees of osteoid matrix maturation and mandibular bone fibrosis were also frequently noted.…”

Section: Discussionsupporting

confidence: 88%

Periodontitis in sheep in Pernambuco, Northeastern Brazil

et al. 2022

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Cases of periodontitis in sheep from the Agreste and Zona da Mata regions of Pernambuco, Northeastern Brazil, are described. Information on breed, age and sex of affected animals as well as clinical and pathological aspects of the disease were obtained during farm visits. Fifteen animals from a total of 450 Santa Inês sheep, aged between three and twelve years, showed low body condition score, dull coat, and difficulty in feeding followed by pain on palpation of the mandibular region. Physical examination of the oral cavity of affected animals and post mortem findings of slaughtered individuals revealed varying degrees of periodontitis, wear, fracture, mobility, and loss of teeth associated with gingival retraction, presence of biofilm and food packing between incisors, premolars and molars teeth. Increased mandibular volume was observed in eight animals and, in two of them, an abscess fistula, exclusively in mandibular teeth. The occurrence of periodontitis in sheep had not been recorded until now in Northeastern Brazil and, thus, this is the first description of cases in the region.

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Section: Discussionsupporting

confidence: 88%

Periodontitis in sheep in Pernambuco, Northeastern Brazil

et al. 2022

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Pathology of chronic ovine periodontitis

et al. 2022

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Periodontitis is an inflammatory process of infectious origin affecting the teeth and their supporting structures, causing significant economic losses and reducing animal welfare. Bacteria in the gingival biofilm are one of the main factors in initiating inflammatory lesions. Bacteria act directly on tissues or indirectly through substances that cause tissue damage. Studies on the etiopathogenesis of periodontitis in Brazilian sheep herds are scarce. The present study aimed to characterize histologically periodontal lesions of culled sheep from the Brazilian breed, Santa Inês. Periodontal lesions, such as periodontal pockets containing plant tissue and bacteria, replacement of the periodontal ligament by connective tissue and inflammatory cells, superficial pustules, hydropic epithelial degeneration, and epithelium hyperplasia, were observed. Submucosal changes were characterized by granulation tissue, edema, swelling of the endothelial cells, bacteria, and predominantly perivascular lymphoplasmacytic inflammatory infiltrate. In the alveolar bone, osteoclastic resorption and bone apposition were observed. This study revealed subacute to chronic inflammation, alveolar bone resorption, and cortical bone apposition in ovine periodontitis. Thus, these findings can contribute to the evolution of knowledge about the etiopathogenesis of ovine periodontitis and, possibly, the development of measures to control the disease.

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Induction of chronic marginal periodontitis in an experimental sheep model: clinical, radiological and histological evaluation

Cited by 2 publications

References 0 publications

Periodontitis in sheep in Pernambuco, Northeastern Brazil

Periodontitis in sheep in Pernambuco, Northeastern Brazil

Pathology of chronic ovine periodontitis

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