Induced charge electro-osmotic particle separation

Chen, Xiaoming; Ren, Yukun; Hou, Likai; Feng, Xiangsong; Jiang, Tianyi; Jiang, Hongyuan

doi:10.1039/c8nr09148j

Cited by 24 publications

(21 citation statements)

References 32 publications

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“…ICEO flow is the nonlinear fluid electroosmosis that occurs when an applied electric field, either DC or AC, acts upon the ionic charge it induces around a polarizable surface [57,58]. This flow has thus far been mainly studied around the conducting surface of, for example, a metallic electrode or particle, either electrically activated or left floating [59][60][61][62][63][64][65][66][67]. It exhibits a quadratic dependence on the applied electric field and typically consists of a pair of counter-rotating vortices [68][69][70][71].…”

Section: Iceo Flowmentioning

confidence: 99%

Review of nonlinear electrokinetic flows in insulator‐based dielectrophoresis: From induced charge to Joule heating effects

Xuan

2021

Electrophoresis

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Insulator‐based dielectrophoresis (iDEP) has been increasingly used for particle manipulation in various microfluidic applications. It exploits insulating structures to constrict and/or curve electric field lines to generate field gradients for particle dielectrophoresis. However, the presence of these insulators, especially those with sharp edges, causes two nonlinear electrokinetic flows, which, if sufficiently strong, may disturb the otherwise linear electrokinetic motion of particles and affect the iDEP performance. One is induced charge electroosmotic (ICEO) flow because of the polarization of the insulators, and the other is electrothermal flow because of the amplified Joule heating in the fluid around the insulators. Both flows vary nonlinearly with the applied electric field (either DC or AC) and exhibit in the form of fluid vortices, which have been utilized to promote some applications while being suppressed in others. The effectiveness of iDEP benefits from a comprehensive understanding of the nonlinear electrokinetic flows, which is complicated by the involvement of the entire iDEP device into electric polarization and thermal diffusion. This article is aimed to review the works on both the fundamentals and applications of ICEO and electrothermal flows in iDEP microdevices. A personal perspective of some future research directions in the field is also given.

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Section: Iceo Flowmentioning

confidence: 99%

Review of nonlinear electrokinetic flows in insulator‐based dielectrophoresis: From induced charge to Joule heating effects

Xuan

2021

Electrophoresis

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“…The use of a large amount of sheath fluid also significantly increases the operating cost. Other approaches mainly rely on the internally or externally imposed forces, such as inertial,[10] viscoelastic [11], electric [12], acoustic [13], and hybrid forces [14,15]. These approaches can accomplish good separation in many circumstances but may have potential drawbacks when the biological particles are handled.…”

Section: Introductionmentioning

confidence: 99%

Separation of micro and sub‐micro diamagnetic particles in dual ferrofluid streams based on negative magnetophoresis

Xue

Sun

et al. 2020

Electrophoresis

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In the present study, we numerically demonstrate an approach for separation of micro and sub-micro diamagnetic particles in dual ferrofluid streams based on negative magnetophoresis. The dual streams are constructed by an intermediate sheath flow, after which the negative magnetophoretic force induced by an array of permanent magnets dominates the separation of diamagnetic particles. A simple and efficient numerical model is developed to calculate the motions of particles under the action of magnetic field and flow field. Effects of the average flow velocity, the ratio of sheath fluid flow to sample fluid flow, the number of the magnet pair as well as the position of magnet pair are investigated. The optimal parametric condition for complete separation is obtained through the parametric analysis, and the separation principle is further elucidated by the force analysis. The separation of smaller micro and sub-micro diamagnetic particles is finally demonstrated. This study provides an insight into the negative magnetophoretic phenomenon and guides the fabrication of feasible, low-cost diagnostic devices for sub-micro particle separation. Abbreviations: SE, separation efficiencyColor online: See article online to view Figs. 1-4 in color.

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“…Particle separation is an essential process prior to water quality analysis 1 , nanoscale exosomes isolation 2, 3 , early-stage cancer diagnosis 4 , uniform-size (microscale or nanoscale) graphene isolation 5,6 , the transesterification of microalgal lipids to biodiesel 7 and so on 8 . For such purposes, many effective methods of separation have been developed, including acoustic waves 4,9 , dielectrophoresis (DEP) [10][11][12] , magnetism 7,13 , optical field 14,15 , and centrifugation 16 . Although each method has its specific advantages, each is also limited by natural drawbacks.…”

Section: Introductionmentioning

confidence: 99%

“…Centrifugation may also achieve massive particle separation; the high-speed rotation makes it near impossible to integrate it with other platforms 16 . Furthermore, magnetism offers excellent performance in a separation device, but is only suitable for magnetic particles or particles able to be magnetically labelled 7,13 . Moreover, many DEP-based separation devices, aside from suffering the same issue as acoustic separation devices, are unable to avoid the adherent growth of cells or adhesion of particles on the electrodes 11 .…”

Section: Introductionmentioning

confidence: 99%

Physical modeling of the axial pipe-soil interaction for pipeline walking on a sloping sandy seabed

et al. 2019

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Induced charge electro-osmotic particle separation

Abstract: We present a direct particle separation method based on induced charge electro-osmotic vortices in continuous flow.

Cited by 24 publications

References 32 publications

Review of nonlinear electrokinetic flows in insulator‐based dielectrophoresis: From induced charge to Joule heating effects

Review of nonlinear electrokinetic flows in insulator‐based dielectrophoresis: From induced charge to Joule heating effects

Separation of micro and sub‐micro diamagnetic particles in dual ferrofluid streams based on negative magnetophoresis

Physical modeling of the axial pipe-soil interaction for pipeline walking on a sloping sandy seabed

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