Indocyanine green angiography in multifocal posterior pigment epitheliopathy

Uyama, M; Matsunaga, Hiroshi; Matsubara, Takashi; Fukushima, Ichiro; Iwashita, Kenshiro; Kimoto, Takashi; Yamada, Haruhiko; Nagai, Yoshimi

doi:10.1007/978-94-011-5137-5_42

Cited by 1 publication

(1 citation statement)

References 9 publications

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“…The areas of choroidal staining are coherent with areas of RPE leakage on fluorescein angiography (FA; Fig. 1 ), suggesting a possible mechanistic association between the two findings 29 , 30 , 31 . However, not all areas of choroidal staining are contiguous with foci of RPE leaks, showing that the RPE may be able to endure the strain caused by the choroidal dysfunction.…”

Section: Pathogenetic Mechanismsmentioning

confidence: 73%

Central Serous Chorioretinopathy: An Update on the Current State of Management

Kalogeropoulos

Shaw

Skondra

et al. 2023

Klin Monbl Augenheilkd

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Central serous chorioretinopathy (CSCR) is a relatively common retinal disorder that leads to central vision impairment, often with a high recurrence rate. The exact etiology and pathogenetic mechanisms have not been fully elucidated but are likely to be associated with hyperpermeability of the choroidal capillaries and failure of the retinal pigment epithelium (RPE), leading to serous detachment of the neurosensory retina. Multimodal imaging plays a critical role in the diagnostic approach and monitoring of CSCR. Fortunately, the natural course of the disease is usually self-limiting, with spontaneous resolution and total fluid reabsorption. However, some patients may exhibit recurrences or persistent subretinal fluid (chronic CSCR), leading to progressive and irreversible RPE atrophy or photoreceptor damage. Thus, to prevent permanent visual loss, individualized treatment should be considered. Recent developments in the diagnostic and therapeutic approach have contributed to better outcomes in patients with CSCR. More studies are required to improve our understanding of epidemiology, pathogenesis, diagnosis, and treatment, with a significant impact on the management of this challenging clinical entity. The purpose of this review is to summarize the current knowledge about the clinical features, diagnostic workup, and therapeutic approach of CSCR.

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Section: Pathogenetic Mechanismsmentioning

confidence: 73%