Indocyanine green angiography in a case of idiopathic retinal vasculitis, aneurysms and neuroretinitis

Gharbiya, Magda; Pantaleoni, F. Bozzoni; Accorinti, Massimo; Pezzi, Paola Pivetti

doi:10.1038/eye.2000.160

Cited by 11 publications

(6 citation statements)

References 5 publications

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“…Gharbiya et al. 7 examined the parents and a twin sister of 47-year-old patient with IRVAN syndrome and the results were unremarkable. Balaratnasingam et al.…”

Section: Discussionmentioning

confidence: 99%

Comprehensive overview of IRVAN syndrome: a structured review of Case Reports and Case Series

Khan

Shahzad

et al. 2022

Ophthalmol Eye Dis

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Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome is a rare spectrum of retinal vasculitis, aneurysms, and neuroretinitis affecting young individuals in their third decade. Most of our current knowledge is based on case reports, case series, and a handful of collaborative studies. There is much diversity in treatment approaches and outcomes in the reported literature. We have aggregated published case reports and case series into quantitative and narrative synthesis to draw evidence-based conclusions toward clinical features, atypical and rare findings, systemic associations, disease course, and treatment outcomes. The analysis suggested the disease mostly affects young individuals with a female predilection. Anterior chamber and vitreous inflammation are common than previously believed. The most prevalent pattern of retinal vasculitis in IRVAN eyes is mixed vasculitis, followed by arteritis and phlebitis. Most eyes at the time of presentation have capillary nonperfusion and require treatment. Most eyes retain good visual acuity; however, treatment is required to maintain visual function. Intravitreal antivascular endothelial growth factors administered as an adjunct to retinal laser photocoagulation are more likely to improve visual outcomes. Besides, we have discussed the different hypotheses on the etiopathogenesis of the disease and stronger evidence suggests an inflammatory origin of the disease.

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“…Gharbiya et al. 7 examined the parents and a twin sister of 47-year-old patient with IRVAN syndrome and the results were unremarkable. Balaratnasingam et al.…”

Section: Discussionmentioning

confidence: 99%

Comprehensive overview of IRVAN syndrome: a structured review of Case Reports and Case Series

Khan

Shahzad

et al. 2022

Ophthalmol Eye Dis

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“…The idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome, first described by Chang et al in 1995 (1), is a rare, devastating, bilateral condition predominantly affecting young women (2). To date, treatment options to prevent visual loss have been limited by the occurrence of several adverse events and complications.…”

Section: Introductionmentioning

confidence: 99%

Dexamethasone Intravitreal Implant for Idiopathic Retinal Vasculitis, Aneurysms, and Neuroretinitis

Empeslidis

Banerjee

Vardarinos

et al. 2013

European Journal of Ophthalmology

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“…1 Young women are most frequently affected, and most cases are not associated with any systemic disorder. 2,3 The typical features of this condition are prominent multiple aneurysmal dilatations of retinal arterioles, neuroretinitis manifesting as diffuse staining of the optic nerve head in the late fundus fluorescein phase, and extensive nonperfusion of peripheral capillaries. Here, we report an atypical case of IRVAN syndrome, and describe the fundus fluorescein and indocyanine green angiography findings of the disease.…”

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confidence: 99%

An atypical case of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome

Gedik

Yılmaz

Akca

et al. 2004

Eye

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Indocyanine green angiography in a case of idiopathic retinal vasculitis, aneurysms and neuroretinitis

Cited by 11 publications

References 5 publications

Comprehensive overview of IRVAN syndrome: a structured review of Case Reports and Case Series

Comprehensive overview of IRVAN syndrome: a structured review of Case Reports and Case Series

Dexamethasone Intravitreal Implant for Idiopathic Retinal Vasculitis, Aneurysms, and Neuroretinitis

An atypical case of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome

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