Indirect spectrophotometric methods for the determination of antibiotics with iodine or periodate, and metol and sulphanilamide

Sastry, C. S. P.; Divakar, T.E.; Prasad, U. Viplava

doi:10.1016/0039-9140(86)80034-0

Cited by 17 publications

(6 citation statements)

References 5 publications

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“…The selectivity of the reaction may increase by using appropriate organic solvent as an extractant, which then depends upon parameters such as the polarities of the amine and of the dye. Several acidic dyes belonging to different chemical classes have been used for the assay of basic drugs [1][2][3][4] . According to the same principle, basic dyes 5 can be used for the assay of acidic drugs.…”

Section: Resultsmentioning

confidence: 99%

Estimation of terbinafine HCL by spectophotometric analysis with Tpooo, Nb12br and WFB

Rao¹,

Sastry²

2022

World J. Chem. Pharm. Sci.

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One simple and sensitive procedure (simple spectrophotometric method) for the assay of drug Terbinafine HCl in pure form and formulations. This method involves the formation of ion-association complex between TRB and the TPOOO, NB12BR and WFB. In order to establish the optimum conditions necessary for rapid and quantitative formation of coloured product with maximum stability and sensitivity, the author performed experiments by measuring the absorbance at λmax 480nm,420nm and580nm of respective series of solutions, varying one and fixing the other parameters in each case such as type, volume and concentration of acid, organic solvent used for extraction, ratio of organic phase to aqueous phase during extraction, shaking time and temperature. The variable parameters were optimized. The results were statistically validated.

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Section: Resultsmentioning

confidence: 99%

Estimation of terbinafine HCL by spectophotometric analysis with Tpooo, Nb12br and WFB

Rao¹,

Sastry²

2022

World J. Chem. Pharm. Sci.

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“…Molecular complex between sulphanilamide and metol, is used for the determination of the antibiotics dihydrostreptomycin, framycetin, and the acid hydrolysis product of chloramphenicol [58] followed by absorbance measurements at 520 nm. The procedure involves periodate oxidation of antibiotics followed by masking periodate excess by molybdates.…”

Section: Charge Transfer Complex Methodsmentioning

confidence: 99%

Periodate oxidation and its contribution to instrumental methods of micro-analysis—A review

Vlessidis

Evmiridis

2009

Analytica Chimica Acta

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“…Several analytical methods were reported for determination of griseofulvin including spectrophotometry (Sastry et al 1986;Eladl 1993;Sastry et al 1998), thin-layer chromatography (Fischer and Riegelman 1966), gas chromatography (Kamimura et al 1979), liquid chromatography (Rundberget and Wilkins 2002), gas-liquid chromatography (Iguchi et al 1966), highperformance liquid chromatography (Zia et al 1980;Kreuzig 1979;Hackett and Dusci 1978), and PMR (Aboutabl and Hassan 1980). To date, no voltammetric procedure for assay of griseofulvin is found in literature.…”

Section: Introductionmentioning

confidence: 98%

A Validated Voltammetric Procedure for Quantification of the Antifungal Drug Griseofulvin in Bulk Form, Tablets, and Biological Fluids at a Mercury Electrode

El‐Desoky

2005

Analytical Letters

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Griseofulvin is an antifungal antibiotic used to treat various pathogenic mycotic diseases. The voltammetric behavior of griseofulvin at a hanging mercury drop electrode in Britton-Robinson buffers of pH 2 -11.5 was studied and discussed. A fully validated sensitive square-wave adsorptive cathodic stripping voltammetric procedure was described for direct determination of bulk griseofulvin substance. The procedure was based on the reduction of the .C5 5O double bond of griseofulvin molecule following its preconcentration onto a hanging mercury drop electrode in a Britton-Robinson buffer of pH 10. Limits of detection (LOD) and quantitation (LOQ) of 5.8 Â 10 210 M and 1.93 Â 10 29 M bulk griseofulvin were achieved, respectively. The proposed stripping voltammetric procedure was successfully applied to assay griseofulvin in tablets and in spiked human serum and urine samples. LOD of 8.65 Â 10 210 M and 6.6 Â 10 29 M and LOQ of 2.88 Â 10 29 M and 2.2 Â 10 28 M griseofulvin in spiked human serum and urine samples, respectively, were achieved.

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Indirect spectrophotometric methods for the determination of antibiotics with iodine or periodate, and metol and sulphanilamide

Cited by 17 publications

References 5 publications

Estimation of terbinafine HCL by spectophotometric analysis with Tpooo, Nb12br and WFB

Estimation of terbinafine HCL by spectophotometric analysis with Tpooo, Nb12br and WFB

Periodate oxidation and its contribution to instrumental methods of micro-analysis—A review

A Validated Voltammetric Procedure for Quantification of the Antifungal Drug Griseofulvin in Bulk Form, Tablets, and Biological Fluids at a Mercury Electrode

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