Increasing the Oxidative Stability of Liquid and Dried Tuna Oil-in-Water Emulsions with Electrostatic Layer-by-Layer Deposition Technology

Abstract

Omega-3 Fatty acids have numerous health benefits, but their addition to foods is limited by oxidative rancidity. Engineering the interfacial membrane of oil-in-water emulsion droplets to produce a cationic and/or thick interface is an effective method to control lipid oxidation. Cationic and thick emulsion droplet interfacial membranes can be produced by an electrostatic layer-by-layer deposition technique resulting in droplets that are coated by multiple layers of emulsifiers. Tuna oil-in-water emulsion droplets coated by lecithin and chitosan produce cationic emulsion droplets that are more oxidatively stable than emulsions coated by lecithin alone. Ethylenediaminetetraacetic acid (EDTA) was able to increase the oxidative stability of emulsions stabilized with lecithin and chitosan more effectively than mixed tocopherols. The combination of EDTA and mixed tocopherols was not more effective than EDTA alone suggesting that control of prooxidant metals was the most important antioxidant technology. The production of emulsion droplets coated with lecithin and chitosan could be an excellent technology for stabilization of oxidatively unstable lipids for use in a variety of food products.

Preparation of coffee oil-algae oil-based nanoemulsions and the study of their inhibition effect on UVA-induced skin damage in mice and melanoma cell growth

“…[10][11][12] DHA, a kind of ω-3 fatty acids, is present in abundant amount in both fish oil and algae oil. However, there is a lack of data regarding the inhibition effect of algae oil on melanoma cells as well as protection effect on UV-induced skin damage in mice.…”

Polymeric Multilayer Capsules in Drug Delivery

“…The resulting emulsions have a rather broad size distribution [81] and can be subjected to further homogenization. [82,83] More recently, microfluidic emulsification has emerged as the most straightforward method to generate monodisperse emulsions. [84] Stabilization of oil droplets is performed by adding an amphiphile to the oil/water emulsion.…”

Wirkstoffverabreichung mithilfe polymerer Mehrschichtkapseln

“…Die Tröpfchen in den erhaltenen Emulsionen weisen eine ziemlich breite Größenverteilung auf, [81] die Emulsion kann aber weiter homogenisiert werden. [82,83] In neuerer Zeit hat sich das Mikrofluid-Emulgieren als das einfachste Verfahren zur Herstellung monodisperser Emulsionen herausgestellt. [84] Zunächst werden dabei die Öltröpfchen stabilisiert, indem der Öl/Wasser-Emulsion ein amphiphiler Stoff zugesetzt wird.…”

“…Um die mehrfache Beschichtung der Tröpfchen zu erleichtern, ist ein ionisches Detergens zu bevorzugen, das den Tröpfchen eine hinreichende Oberflächenladung verleiht. Es wurde über Proteine, [85] kationische [81,86] und anionische Lipide [82] sowie amphiphile Polymere [86] [67] C) Laserinduziertes Mischen der Bestandteile beider Kompartimente der PMLCs. Die inneren und äußeren Hüllen sind schematisch durch schwarze Kreise wiedergegeben.…”