Increasing incidence of childhood-onset type 1 diabetes mellitus among Estonian children in 1999-2006. Time trend analysis 1983-2006

Abstract

The incidence of childhood-onset T1DM in Estonia continues to rise and the age of onset of the disease becomes younger.

An increasing incidence of type 1 diabetes mellitus in Romanian children aged 0 to 17 years

“…The incidence of type 1 diabetes mellitus increased in the age groups 0-4, 5-9, and 10-14 years; the highest rate of increase was recorded for the youngest children. This was a finding in many epidemiological studies (4,11,16), but not in all (17). By contrast, the incidence of type 1 diabetes mellitus decreased in children aged 15-17 years.…”

“…We found the lowest incidence in the subgroup 0 to 4 years, and the highest in children aged between 10 and 14 years. The differences between the age groups were mentioned by many other authors (7,8,11), but some of them found the highest incidence in children aged 5-9 years.…”

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

“…In nearby Estonia, coinciding with economic development and improvement in living standards, the incidence of T1D and atopy has been transitioning in recent decades from rates similar to those of Russian Karelia toward those of Finland (Teeaar et al, 2010; Voor et al, 2005). Using these three populations as a “living laboratory,” the DIABIMMUNE study (http://www.diabimmune.org/) recruited a total of ~1,000 infants from Espoo (Finland), Petrozavodsk (Russia), and Tartu (Estonia).…”

The incidence of type 1 diabetes mellitus among 15-34 years aged Lithuanian population: 18-year incidence study based on prospective databases

“…The rising incidence of type 1 diabetes globally suggests the need for continuous monitoring of incidence by using standardized methods in order to plan or assess prevention strategies [7]. Epidemiological studies of type 1 diabetes mellitus in the Baltic Sea Basin population are important because of the large variation in childhood onset diabetes incidence recorded over the region [8,25-27]. The average of 24-year (1983-2007) type 1 diabetes incidence rates among 0-4, 5-9, 10-14, and all 0-14-year-aged Lithuanian children was 4.9, 9.1, 11.4, and 8.8 per 100,000 persons per year, respectively (5.3, 7.8, 12.2, 8.6 and 4.6, 10.3, 11.7, 8.4 per 100,000 persons per year among boys and girls, respectively).…”