Increased Tei Index Suggests Absence of Adequate Coronary Reperfusion in Patients With First Anteroseptal Acute Myocardial Infarction

Kuwahara, Eiji; Takasaki, Kunitsugu; Yuasa, Toshinori; Kumanohoso, Toshiro; Nakashima, Hitoshi; Toyonaga, Kenji; Shiro, Yoshitsugu; Miyata, Masaaki; Hamasaki, Shuichi; Lee, Souki; Kisanuki, Akira; Minagoe, Shinichi

doi:10.1253/circj.70.248

Cited by 7 publications

(3 citation statements)

References 42 publications

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“…It is simple, noninvasive, easy to use and reproducible. Moreover, the calculation of the Tei index is independent of age, arterial pressure, heart rate, ventricular geometry, atrioventricular valve regurgitation, afterload, and preload in patients who are in a supine position [5,17,28,31,32] .…”

Section: Discussionmentioning

confidence: 99%

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Global left ventricular performance in non-diabetic non-hypertensive metabolic syndrome adults

Sliem

Nasr²,

Ibrahiem³

2011

WJC

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AIM:To evaluate the left ventricular structure and function in isolated metabolic syndrome. METHODS:One hundred and fifty six consecutive adults with metabolic syndrome were enrolled in the study. Fifty nine had isolated metabolic syndrome (group A) and 97 had metabolic syndrome with hypertension and/or diabetes (group B). There was a control group of 34 healthy adults. In addition to classic echocardiographic assessment of myocardial structural and functional changes, the Tei index was used to evaluate global left ventricular performance. RESULTS:There were no statistically significant differences between group A and controls in all parameters of left ventricular structural, systolic, and diastolic function except global myocardial performance (Tei index). On the other hand, significant differences were observed between group B and the control group in most of the parameters of left ventricular structural and global performance. CONCLUSION:The early identification of isolated metabolic syndrome in non-diabetic, non-hypertensive adults may be an indication that aggressive preventive measures should not be postponed until overt obesity, hypertension or diabetes mellitus has developed.

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Section: Discussionmentioning

confidence: 99%

“…A Tei index < 0.40 is considered normal. Higher index values correspond to more pathological states with overall cardiac dysfunction [17] .…”

Section: Echocardiographic Evaluationmentioning

confidence: 99%

Global left ventricular performance in non-diabetic non-hypertensive metabolic syndrome adults

Sliem

Nasr²,

Ibrahiem³

2011

WJC

View full text Add to dashboard Cite

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“…This index was found to be related to morbidity and mortality in patients with various cardiac diseases, and correlated with invasive measurements of LV systolic and diastolic function. [32][33][34][35] In the present study, the effect of menopause on cardiac functions was evaluated by the analysis of all myocardial segmental velocities obtained by TDE. Age-related bias on cardiac functions was overcome by selecting pre-and postmenopausal women from the same age group.…”

Section: Circulation Journal Vol71 November 2007mentioning

confidence: 99%

Effects of Menopause on the Myocardial Velocities and Myocardial Performance Index

Düzenli

Özdemi̇r

Sökmen

et al. 2007

Circ J

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enopause is a critical period in a woman's life, during which many physiologic and pathologic changes occur. Women spend one-third of their lifetime in this period and the hormonal changes that occur during this period have significant influences on several organs and systems. The cardiovascular system is among the most dramatically affected systems. Changes in cardiovascular risk factors due to estrogen deficiency and subsequent increase in cardiovascular morbidity and mortality have been demonstrated in several studies. [1][2][3] Structural and functional changes in the heart can also occur during the postmenopausal period. The effects of menopause on cardiac structure and function have not been investigated adequately. Interpretation of the results of the few previous studies 4-6 comparing pre-and postmenopausal women comprises some difficulties, owing to significant age differences and small sample sizes. Moreover, cardiac functions have been evaluated only by conventional 2-dimensional (D) and M-mode echocardiography in these studies, thus the extent of influence on more recent echocardiographic parameters after menopause have not been adequately analyzed.Tissue Doppler echocardiography (TDE) is a relatively new technique, which is partially utilized in recent years to evaluate cardiac functions via measurement of myocardial velocities. 7 Also, myocardial performance index (MPI) has been recognized as a parameter that reflects ventricular systolic and diastolic functions. 8,9 To our knowledge, no literature exists on how myocardial velocities, as measured by TDE, which have some advantages over standard echocardiographic methods, and MPI, which provides a more quantitative and global evaluation of left ventricular (LV), are affected by menopause. The present study was designed to investigate how myocardial velocities measured by TDE and MPI, which together provide more quantitative data on regional and global ventricular functions, are affected by menopause. Methods Study PopulationSubjects were selected from healthy women admitted to the gynecology and obstetrics, and cardiology outpatient departments between 2001 and 2006. After informed consent was obtained, a prospective analysis was performed. Body weight and height of all subjects were measured and body mass index was calculated. Fasting blood samples were drawn for biochemical and hematological investigations and ECGs were done. An exercise stress test using Bruce protocol and subsequent echocardiographic evaluations were performed. Postmenopausal status was confirmed as being in menopause for at least 12 months with serum follicle-stimulating hormone (FSH) levels of >30 mU/ml and estrogen levels of <20 pg/ml, and premenopausal status Effects of Menopause on the Myocardial Velocities and Myocardial Performance IndexMehmet Akif Düzenli, MD; Kurtulus Ozdemir, MD; Abdullah Sokmen, MD**; Ahmet Soylu, MD; Nazif Aygul, MD; Kazim Gezginc, MD*; Mehmet Tokac, MD Background Although menopause is known to increase cardiovascular risk and mortality, the effect ...

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Effect of reperfusion therapy on index of myocardial performance in acute myocardial infarction: thrombolytics versus primary angioplasty

et al. 2010

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It is known that primary angioplasty is more effective than thrombolytic therapy for the treatment of ST-segment elevation acute myocardial infarction. The aim of the present study is to compare the effects of the two strategies on the left ventricular functions using the Tei index (a combined myocardial performance index). Of 81 patients (11 female, mean age 52.7 +/- 11.9 years, and 70 male, mean age 54.8 +/- 11.5 years) matching the selection criteria, 41 patients were treated by primary percutaneous transluminal coronary angioplasty and stenting (group A, 41 patients) and 40 patients were treated by thrombolytic agents (streptokinase) (group B, 40 patients). All patients underwent a complete two-dimensional transthoracic echocardiographic and Doppler study in the left lateral decubitus position from multiple windows. There was no significant difference between the two groups in isovolumetric contraction time and ejection time. Isovolumetric relaxation time was 95.2 +/- 18.4 in group A and 116.2 +/- 28.1 in group B (P = 0.001) and the Tei index was 0.51 +/- 0.12 in group A and 0.59 +/- 0.16 in group B (P = 0.019). Isovolumetric relaxation time and Tei index were significantly higher in group B. Primary angioplasty is superior to thrombolytic therapy as assessed by the Tei index even in the first 3 h, with no apparent change in systolic function.

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Increased Tei Index Suggests Absence of Adequate Coronary Reperfusion in Patients With First Anteroseptal Acute Myocardial Infarction

Abstract: An increased Tei index suggests the absence of adequate coronary reperfusion in patients with first anterior AMI without other lesion.

Cited by 7 publications

References 42 publications

Global left ventricular performance in non-diabetic non-hypertensive metabolic syndrome adults

Global left ventricular performance in non-diabetic non-hypertensive metabolic syndrome adults

Effects of Menopause on the Myocardial Velocities and Myocardial Performance Index

Effect of reperfusion therapy on index of myocardial performance in acute myocardial infarction: thrombolytics versus primary angioplasty

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