Increased serum amylase levels in prostatic diseases

Hanafy, Hanafy Mohamed; Gursel, Erol O.; Veenema, Ralph J.

doi:10.1016/0090-4295(73)90292-6

Cited by 14 publications

(5 citation statements)

References 7 publications

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“…It was found that the prostatic fluid contains more amylase than the seminal vesicle fluid (9). We have previously reported our results o f serum amylase level in prostatic disease (5,6).…”

Section: Introductionmentioning

confidence: 53%

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Possible Role of Amylase Enzyme in Prostatic and Seminal Fluid

Hanafy¹

1979

Urol Int

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“…It was found that the prostatic fluid contains more amylase than the seminal vesicle fluid (9). We have previously reported our results o f serum amylase level in prostatic disease (5,6).…”

Section: Introductionmentioning

confidence: 53%

“…Hanafy et al (5) localized the amylase in prostatic secretions from malig nant prostate by histochemical method.…”

Section: Discussionmentioning

confidence: 99%

Possible Role of Amylase Enzyme in Prostatic and Seminal Fluid

Hanafy¹

1979

Urol Int

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“…The similarity in the serum amylase activity from rats across dietary treatments could be interpreted to mean that defatted XCKM could substitute SBM as a dietary protein source in rat (and probably other monogastric animal) diets without eliciting salivary and exocrine pancreatic gland disorders (Suehiro et al., ). Defatted XCKM could also substitute SBM without causing overt pulmonary disease (Otsuki et al., ) and renal failure (Hanafy et al., ). Serum amylase activity is elevated in pancreatic and salivary gland disorders (Suehiro et al., ), pulmonary disease (Weiss et al., ; Otsuki et al., ) and renal failure (Hanafy et al., ); thus, determination of serum amylase activity is used in the general assessment of the health status of animals.…”

Section: Discussionmentioning

confidence: 99%

“…Defatted XCKM could also substitute SBM without causing overt pulmonary disease (Otsuki et al., ) and renal failure (Hanafy et al., ). Serum amylase activity is elevated in pancreatic and salivary gland disorders (Suehiro et al., ), pulmonary disease (Weiss et al., ; Otsuki et al., ) and renal failure (Hanafy et al., ); thus, determination of serum amylase activity is used in the general assessment of the health status of animals. Dietary composition (ingredient and chemical composition) has been reported to influence the synthesis, storage and secretion of digestive enzymes by the exocrine pancreas (Sabb et al., ; Dubick et al., ).…”

Section: Discussionmentioning

confidence: 99%

Effect of dietary Ximenia caffra kernel meal on blood and liver metabolic substrate content and the general clinical biochemistry of Sprague Dawley rats

Chivandi

Moyo

Dangarembizi

et al. 2015

Animal Physiology Nutrition

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We investigated (at the University of the Witwatersrand: GPS coordinates 26°10' 52.96″S; 28°2' 33.61″E) the effects of substituting soya bean meal (SBM) with Ximenia caffra kernel meal (XCKM) as a dietary protein source on blood and liver metabolic substrates content, serum markers of liver and kidney function and the general clinical biochemistry of Sprague Dawley (SD) rats. Five diets with similar energy and protein content were formulated (D1-D5) where XCKM replaced SBM on a crude protein basis at 0, 25, 50, 75 and 100%. Forty weanling male SD rats were randomly assigned to diets D1-D5, fed for 37 days and weighed twice weekly. The rats were then fasted overnight, and fasting blood glucose and triglyceride concentrations were determined from tail-vein-drawn blood. Immediately thereafter, the rats were euthanised and blood was collected via cardiac puncture. Serum was used to assay for markers of the general health profile. Livers were removed and weighed, and samples were used to determine lipid and glycogen content. Rats fed D4 (75% substitution level) had significantly lower (p < 0.05) blood triglyceride content compared with rats fed D2 (25% level of substitution). The substitution of SBM with XCKM did not affect (p > 0.05) fasting blood glucose and cholesterol concentrations, liver glycogen and lipid content. Additionally, it had no effect (p > 0.05) on serum activity/concentration of surrogate markers of liver (alanine aminotransferase and alkaline phosphatase activity and urea, total bilirubin, globulin and albumin concentrations) and kidney (phosphorus, calcium and creatinine concentrations) function and the general clinical biochemistry of the rats. Defatted XCKM could substitute SBM in rat diets without compromising blood glucose and cholesterol homeostasis, liver and kidney function and the general clinical biochemistry of growing male Sprague Dawley rats.

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“…Amylase can be categorized into two types: pancreatic amylase and salivary amylase, accounting for approximately 40%-45% and 55%-60% of total amylase, respectively [26] . Elevated amylase levels are associated with various benign and malignant conditions, including acute pancreatitis, pancreatic pseudocysts, perforated ulcer, intestinal infarctions, ascites, acute cholecystitis, ruptured ectopic pregnancy, peritonitis, diabetic ketoacidosis, salivary gland diseases, and multiple types of malignancies such as breast [27] , lung [28] , prostate [29] , and ovarian cancers [4,30,31] . Low amylase levels can be attributed to chronic pancreatitis causing permanent cell damage, kidney disease, cystic fibrosis, liver disease, or pre-eclampsia [32] .…”

Section: Amylase Levelsmentioning

confidence: 99%

Oxidative enzymes and vitamin E in ovarian cancer: Insights from a case-control study

AL-dulaimy,

Mohammed,

Hassuby

et al. 2023

Trends Immunother.

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Studying vitamin E’s antioxidant capabilities and how they relate to oxidative enzymes in the context of ovarian cancer was the focus of this study. A case-control study was conducted, with 100 women with ovarian cancer serving as cases and 30 women in good health serving as controls. Enzyme-linked immunosorbent assay (ELISA) was used to assess serum levels of trypsin, chymotrypsin, pancreatic-type amylase, and vitamin E, while the dimercaptopropanol tributyrate (BALB) method was used to measure lipase levels. Patients with ovarian cancer were shown to have lower levels of chymotrypsin and lipase and higher levels of trypsin and amylase than controls. The two groups had almost the same vitamin E content. According to these findings, oxidative enzymes may have a role in the progression of ovarian cancer by increasing trypsin and amylase and decreasing chymotrypsin and lipase. Although vitamin E was thought to slow the development of gynecologic malignancies, the study found no such impact. Further research with larger study groups is necessary to obtain more robust results.

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Increased serum amylase levels in prostatic diseases

Cited by 14 publications

References 7 publications

Possible Role of Amylase Enzyme in Prostatic and Seminal Fluid

Possible Role of Amylase Enzyme in Prostatic and Seminal Fluid

Effect of dietary Ximenia caffra kernel meal on blood and liver metabolic substrate content and the general clinical biochemistry of Sprague Dawley rats

Oxidative enzymes and vitamin E in ovarian cancer: Insights from a case-control study

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