Increased pulse wave velocity and carotid intima–media thickness in patients with carpal tunnel syndrome

Abstract

There is both increased pulse wave velocity and CIMT and a positive correlation between these parameters and median nerve sensory distal latency in patients with CTS. CTS appears to be associated with arterial stiffness and atherosclerotic burden, but the underlying mechanisms require further study.

Smoking and carpal tunnel syndrome: A meta‐analysis

“…Smoking may cause peripheral neuropathy through toxic effects, or it may impair recovery following peripheral nerve injury . More recent studies suggested that smoking may cause CTS through atherosclerosis …”

Association Between Cardiovascular Risk Factors and Carpal Tunnel Syndrome in Pooled Occupational Cohorts

“…3,[21][22][23][24][25][26][27][28][29] This is particularly suggested by both the data on metabolic syndrome [26][27][28] and insulin resistance 30 as well as a few retrospective studies suggesting an association with carotid intima-media thickness. [31][32][33] CVD disease association has been further suggested by a protective effect of vigorous exercise with and without wrist strain reported in a case-control study. 34 As both obesity and diabetes appear to be risk factors, this also suggests a potential relationship with CVD disease.…”

Reply

“…We thank Drs. Varol and Ozaydin for their interest and for their valuable remarks on our article . We agree that the major determinants of arterial stiffness are aging and hypertension .…”