Increased house dust mite allergen in synthetic pillows may explain increased wheezing

Crane, Julian; Kemp, Trudi; Siebers, Robert; Rains, Natalie; Fishwick, David; Fitzharris, Penny

doi:10.1136/bmj.314.7096.1763b

Cited by 14 publications

(10 citation statements)

References 4 publications

(4 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, synthetic bedding has been suggested as a risk factor for all atopic disease in a recent German study 20 . Specifically, three previous studies have found a positive association between the use of synthetic pillows and asthma 21–23 . Subsequent studies demonstrating increased house dust mite and pet allergen in synthetic pillows may explain such associations 22,24–26 .…”

Section: Discussionmentioning

confidence: 96%

“…Specifically, three previous studies have found a positive association between the use of synthetic pillows and asthma 21–23 . Subsequent studies demonstrating increased house dust mite and pet allergen in synthetic pillows may explain such associations 22,24–26 . A clinical trial of house dust mite eradication in the home suggested that just plain vacuum cleaning in the control group had a beneficial effect in atopic eczema alone 27 …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Atopic eczema and the home environment

McNally

Williams

Phillips³

2001

Br J Dermatol

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Atopic eczema and the home environment

McNally

Williams

Phillips³

2001

Br J Dermatol

View full text Add to dashboard Cite

show abstract

“…Therefore, the microbial milieu within the animal fur is suggested to be dependent on the home environment, housing and personal characteristics of the inhabitants [30,31]. In addition to this, the use of synthetic bedding above feather bedding has been considered as a possible risk factor for respiratory symptoms in children in some previous studies due to higher levels of mite allergens [32,33]. Unfortunately, we were not able to test whether the type of bedding material may confound the association between sleeping on animal fur in the first 3 months of life and later respiratory outcomes as a major extent of the included children used different type of materials for bedding simultaneously.…”

Section: Discussionmentioning

confidence: 99%

Sleeping on animal fur is related to asthma outcomes in later childhood

et al. 2015

View full text Add to dashboard Cite

Animal furs might represent a "proxy" for high and diverse microbial exposures within a critical time window of immune development. We assessed whether sleeping on animal fur shortly after birth is associated with asthma and atopy up to the age of 10 years.LISAplus participants (n=2441) from Munich and Leipzig, Germany, were included in the analysis. Animal fur exposure, cofactors and health outcomes were obtained periodically up to 10 years of age by parental questionnaires. Information on specific IgE to aeroallergens was available at 10 years. Cytokineproducing peripheral T-cells were assessed in a subgroup of children at 2 and 3 years. Confounderadjusted associations were evaluated using logistic regression analyses.Sleeping on animal fur was very common (55%). In adjusted logistic regression analyses, sleeping on animal fur was inversely associated with recurrent early wheezing at 4 years (adjusted OR 0.75, 95% CI 0.61-0.93) and current asthma at 6 years (adjusted OR 0.56, 95% CI 0.31-1.01). Furthermore, sleeping on animal fur during the first 3 months of life was significantly associated with a persistently stimulated interferon-γ response until the age of 3 years.Animal fur could be an effective measure of creating environments associated with higher microbial exposure. @ERSpublications Use of animal fur could be effective for creating environments associated with possibly higher microbial exposure http://ow.ly/IWhTp

show abstract

“…Feather-based bedding has been associated with lower levels of HDM allergen compared with synthetic bedding [11, 12]. A recent randomized controlled trial studied 197 HDM-sensitized moderate to severe asthmatic children to examine the difference between feather bedding and HDM bedding covers.…”

Section: Dust Mitementioning

confidence: 99%

Impact of Environmental Controls on Childhood Asthma

Rao

Phipatanakul

2011

Curr Allergy Asthma Rep

View full text Add to dashboard Cite

Exposure to allergens early in life can lead to sensitization and the development of childhood asthma. It is thought that increased exposure with the advent of modern housing is likely contributing to the rise in prevalence of childhood asthma during the past few decades. The progression from allergen exposure to sensitization and asthma development has been noted with respect to dust mites, pets, cockroach, mouse, mold, tobacco smoke, endotoxin, and air pollution, although some have found a protective effect with pet and endotoxin exposure. Recent studies have shown that allergen remediation may be beneficial in reducing asthma morbidity and development, although there is also some evidence to the contrary. Examples of allergen remediation that have been studied include the use of dust mite–impermeable covers, high-efficiency particulate air filtration, integrated pest management, home repairs, ventilation improvement, and pet removal. Several multifaceted, randomized controlled trials have shown that reducing multiple early allergen exposures with environmental controls is associated with a decreased risk of asthma.

show abstract

Increased house dust mite allergen in synthetic pillows may explain increased wheezing

Cited by 14 publications

References 4 publications

Atopic eczema and the home environment

Atopic eczema and the home environment

Sleeping on animal fur is related to asthma outcomes in later childhood

Impact of Environmental Controls on Childhood Asthma

Contact Info

Product

Resources

About