Increase in Neuroexcitability of Unmyelinated C‐type Vagal Ganglion Neurons During Initial Postnatal Development of Visceral Afferent Reflex Functions

Abstract

These data demonstrate for the first time that the neuroexcitability of C-type VGNs increases significantly compared with A-types within initial postnatal weeks evidenced by AP discharge profiles and coordinate ion channel changes, which explain, at least in part, that initial postnatal weeks may be crucial for ontogenesis in visceral afferent reflex function.

Direct activation of tachykinin receptors within baroreflex afferent pathway and neurocontrol of blood pressure regulation

“…So, the questions remain about the specific role and significance of SP in baroreflex afferent function and BP regulation under physiological and hypertensive conditions. A large body of evidence from our group has demonstrated sexual dimorphism in baroreflex afferent function [12][13][14][15] and female hormone-dependent BP regulation in rodents. [16][17][18][19] However, the question regarding if estrogen plays a central role in unusual changes of BP associated with tachykinin receptors' (NKRs) expression in baroreflex afferent pathway needs to be answered.…”