“…Collagen sponges applied as daily dressing have given good results in the treatment of surgical wounds of the skin in the rabbit (Collins, Peacock & Chvapil, 1976) and rat (Burgct et al, 1976;Oliver et al, 1977)-They have also been used as daily dressings to speed the healing of dermabrasion wounds (Shekter et al, 1975;Zachariae, 1976), but ours is the first report, so far as we know, of collagen sponges being applied to human leg ulcers and left in situ in an attempt to stimulate the formation of granulation tissue.…”