Incorporating Genomics and Bioinformatics across the Life Sciences Curriculum

Ditty, Jayna L.; Kvaal, Christopher; Goodner, Brad; Freyermuth, Sharyn K.; Bailey, Cheryl; Britton, Robert A.; Gordon, Stuart G.; Heinhorst, Sabine; Reed, Kelyenne; Xu, Zhaohui; Sanders-Lorenz, Erin R.; Axen, Seth D.; Kim, Edwin; Johns, Mitrick A.; Scott, Kathleen M.; Kerfeld, Cheryl A.

doi:10.1371/journal.pbio.1000448

Cited by 57 publications

(44 citation statements)

References 36 publications

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“…In general, Science creates new knowledge in a particular way, by employing the scientific method based on experimental verification of hypotheses and rigorous validation of results by peer groups. As bioinformatics is generated [16], new disciplines emerge in science e.g. clinical biochemistry to confirm the importance of bioinformatics and to enhance the accuracy of the bioinformatics results.…”

Section: Integrative Aspects Of Clinical Biochemistrymentioning

confidence: 99%

Contribution of Clinical Biochemistry to Structural Bioinformatics

Afify¹

2016

Am. J. Biomed. Sci.

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Bioinformatics plays an important role in the study of human diseases with genomic data for drug development and gene therapy. Its applicative arm is clinical biochemistry that focuses on the methodology and interpretation of chemical tests performed to support diagnosis and treatment. Clinical biochemistry is one of the most important parts of laboratory diagnostics tests together with laboratory hematology, immunology, clinical serology and microbiology, clinical toxicology. It possesses the largest number of diagnostic tests that help to understand pathogenesis and etiology of different pathological processes. Clinical biochemistry is based on bioinformatics applications that have been used for tumor marker measurements, stem cell tests, gene expression, and DNA damage repair. Bioinformatics field can be derived from biochemistry. It means that biochemistry has emerged from bioinformatics applications. It is not an overstatement to say that bioinformatics is what biochemistry is evolving to become a distinct guide for quality control. This paper focuses on the point of contemporary clinical biochemistry that tends to support bioinformatics researchers. Integration between biochemistry and bioinformatics would lead to an increase in healthcare performance is thus of increasing importance in future research.

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Section: Integrative Aspects Of Clinical Biochemistrymentioning

confidence: 99%

Contribution of Clinical Biochemistry to Structural Bioinformatics

Afify¹

2016

Am. J. Biomed. Sci.

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“…However, bioinformatics is complex and multidisciplinary, requiring expertise from biology, physical chemistry, maths, computer science, and statistics [12]. Thus, several authors now acknowledge that teaching fundamental concepts and developing basic bioinformatics skills is essential curriculum for life science students [8,[13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Implementing a web‐based introductory bioinformatics course for non‐bioinformaticians that incorporates practical exercises

Vincent

Bourbonnais

Brouard

et al. 2017

Biochem Molecular Bio Educ

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A recent scientific discipline, bioinformatics, defined as using informatics for the study of biological problems, is now a requirement for the study of biological sciences. Bioinformatics has become such a powerful and popular discipline that several academic institutions have created programs in this field, allowing students to become specialized. However, biology students who are not involved in a bioinformatics program also need a solid toolbox of bioinformatics software and skills. Therefore, we have developed a completely online bioinformatics course for non‐bioinformaticians, entitled “BIF‐1901 Introduction à la bio‐informatique et à ses outils (Introduction to bioinformatics and bioinformatics tools),” given by the Department of Biochemistry, Microbiology, and Bioinformatics of Université Laval (Quebec City, Canada). This course requires neither a bioinformatics background nor specific skills in informatics. The underlying main goal was to produce a completely online up‐to‐date bioinformatics course, including practical exercises, with an intuitive pedagogical framework. The course, BIF‐1901, was conceived to cover the three fundamental aspects of bioinformatics: (1) informatics, (2) biological sequence analysis, and (3) structural bioinformatics. This article discusses the content of the modules, the evaluations, the pedagogical framework, and the challenges inherent to a multidisciplinary, fully online course. © 2017 by The International Union of Biochemistry and Molecular Biology, 46(1):31–38, 2018.

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“…But the main problem nowadays is how to train interdisciplinary scientists, that is, how to train individuals that can communicate efficiently with scientists of other fields. There is a lot of theoretical work on how a Bioinformatics curriculum should be built, combining elements of the «mother» disciplines, and several approaches have been described to incorporate Bioinformatics training in the Biological, Medical or Computer Science curriculum (Altman, 1998;Ditty et al, 2010;Floriano, 2008;Honts, 2003;Searls, 2012;Welch et al, 2014;Yan, et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Bioinformatics Education in Greece: A Survey

Paraskevopoulou-Kollia

Bagos

2017

J Bio Bio Edu

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Bioinformatics is an interdisciplinary field, placed at the interface of Biology, Mathematics and Computer Science. In this work, we tried for the first time to investigate the current situation of Bioinformatics education in Greece. We searched the online resources of all relevant University Departments for Bioinformatics or relevant courses. We found that all the Departments of Biological Sciences include in their curricula courses dedicated to Bioinformatics, but this is not the case for Departments of Computer Science, Computer Engineering, or Medical Schools. Despite the fact that large Universities played a crucial role in establishing Bioinformatics research and education in Greece, we observe that Universities of the periphery invest in the field, by including more relevant courses in the curricula and appointing faculty members trained in the field. In order for us to "triangulate" we didn't confine ourselves to online resources and descriptive statistics but we also included interviews so as to have a more spherical view of the subject under discussion. The interviews provided useful insights regarding the teaching methods used by bioinformatics tutors, their attitudes and the difficulties they encounter. The tutors mentioned also the material that they choose, the audience's attraction techniques and the feedback they receive.

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Incorporating Genomics and Bioinformatics across the Life Sciences Curriculum

Cited by 57 publications

References 36 publications

Contribution of Clinical Biochemistry to Structural Bioinformatics

Contribution of Clinical Biochemistry to Structural Bioinformatics

Implementing a web‐based introductory bioinformatics course for non‐bioinformaticians that incorporates practical exercises

Bioinformatics Education in Greece: A Survey

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