Contribution of Clinical Biochemistry to Structural Bioinformatics

Abstract

Bioinformatics plays an important role in the study of human diseases with genomic data for drug development and gene therapy. Its applicative arm is clinical biochemistry that focuses on the methodology and interpretation of chemical tests performed to support diagnosis and treatment. Clinical biochemistry is one of the most important parts of laboratory diagnostics tests together with laboratory hematology, immunology, clinical serology and microbiology, clinical toxicology. It possesses the largest number of diagnostic tests that help to understand pathogenesis and etiology of different pathological processes. Clinical biochemistry is based on bioinformatics applications that have been used for tumor marker measurements, stem cell tests, gene expression, and DNA damage repair. Bioinformatics field can be derived from biochemistry. It means that biochemistry has emerged from bioinformatics applications. It is not an overstatement to say that bioinformatics is what biochemistry is evolving to become a distinct guide for quality control. This paper focuses on the point of contemporary clinical biochemistry that tends to support bioinformatics researchers. Integration between biochemistry and bioinformatics would lead to an increase in healthcare performance is thus of increasing importance in future research.