Inclusion Complexation of Cholestanol, Cholesterol, Sitosterol, Stigmasterol, and Ergosterol with Various Guest Compounds

Abstract

The title steroids were found to form crystalline inclusion complexes with a wide variety of guest compounds. Crystal structures, interaction modes and molecular recognition features of selected host-guest systems have been characterized.

Steroids in Molecular Recognition

“…Not much is known about the inclusion complex forming abilities of other steroids. The X-ray crystal structures of cholesterol hydrate and the clathrates with ethanol and other guests have been described …”

“…The X-ray crystal structures of cholesterol hydrate and the clathrates with ethanol and other guests have been described. 369 Also, formation and characterization of clathrates between sitosterol (164), stigmasterol (165), and ergosterol (166) and various guests were reported.…”