Inclusion complexation of chloropropham with β-cyclodextrin: Preparation, characterization and molecular modeling

Ge, Xin; He, Jiang; Qi, Feng‐Ming; Yang, Ying; Huang, Zheng; Lü, Ruitao; Huang, Lijia

doi:10.1016/j.saa.2011.06.028

Cited by 55 publications

(23 citation statements)

References 28 publications

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“…1 H NMR experiments are one of the most important tools to evidence the RCD formation when a molecule is incorporated into the CD cavity. Generally, the hydrogen atoms inside the cavity (H3 and H5) should be sensitive to the change of chemical environment, as previously reported by Ge et al, [17] In general, changes in chemical shift ( ∆δ) were small because the intermolecular interactions between the molecules are of noncovalent nature (e. g. Van der Waals forces, hydrogen bonds, hydrophobic interactions) [18]. H NMR spectra of CD and RCD showed that the chemical shift of some nuclei changed when complex inclusion is formed.…”

Section: Characterization Of the Inclusion Complexsupporting

confidence: 58%

“…Thermo analysis also has been applied to investigate the formation and thermal stability of RCD. The melting point and enthalpy of fusion of the RCD indicate changes in the intermolecular interactions and molecular arrangements in the lattice [17,21]. Data from the differential scanning calorimetry (DSC) and thermogravimetry (TGA) are given in table 3.…”

Section: Characterization Of the Inclusion Complexmentioning

confidence: 99%

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RESVERATROL INCLUSION COMPLEX WITH Β-Cyclodextrin (RCD): CHARACTERIZATION AND EVALUATION OF TOXICITY IN WISTAR RATS

Nishihira

Mezzomo

Baldissera

et al. 2016

Int J Pharm Pharm Sci

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Objective: The aim of this study was to characterise the resveratrol inclusion complex with β-cyclodextrin (RCD) and evaluate their toxicity in wistar rats.Methods: The RCD were prepared in ultra-turrax. For characterization of the RCD were used: Fourier transform infra-red Spectroscopy, Nuclear Magnetic Resonance (NMR), Differential Scanning Calorimetry (DSC) and X-ray powder diffraction. The RCD and others 4 treatments were performed by the chronic oral administration in 35 rats during 60 ds. After the treatments they were euthanized and the serum blood were collected to analyzed some hemogram and biochemical parameters including aspartyl aminotransferase (AST); alanine aminotransferase (AST); phosphatase alkaline (ALP); total bilirubin (TB); direct bilirubin (DB); total protein (TP); total cholesterol (TC), triacylglycerol (TAG), very low-density lipoprotein (VLDL), high-density lipoprotein (HDL), calcium, iron and phosphate using fully automated biochemistry analyzer.Results: The characterization results indicated a successful formation of the RCD. All hematological parameters analysed were within the normal values in all the groups. Furthermore, the hemogram and biochemical parameters were significantly (P>0.05) similar to the control group.Conclusion: The daily oral administration during 60 d of RCD are not harmful on blood parameters of Wistar rats. Thus, RCD can be used safely for treatment of some metabolic diseases.

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Section: Characterization Of the Inclusion Complexsupporting

confidence: 58%

Section: Characterization Of the Inclusion Complexmentioning

confidence: 99%

RESVERATROL INCLUSION COMPLEX WITH Β-Cyclodextrin (RCD): CHARACTERIZATION AND EVALUATION OF TOXICITY IN WISTAR RATS

Nishihira

Mezzomo

Baldissera

et al. 2016

Int J Pharm Pharm Sci

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“…1 HNMR spectroscopy has been previously used to prove the construct of the inclusion complexes between Me‐β‐CD and guest molecules, which further investigate the interactions between the components in solution. When the guest molecule enter the cavity of the Me‐β‐CD, the micro environment of the proton will change, leading to proton chemical shifts or disappear …”

Section: Resultsmentioning

confidence: 94%

Preparation, Characterization and Application of Cyclodextrin‐Containing UV‐Curable Waterborne Polyurethane Based on Guest Regulation

Yao

Shi

et al. 2020

ChemistrySelect

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A novel UV‐curable supramolecular waterborne polyurethane (PU) was prepared through the introduction of methylated‐β‐cyclodextrin (Me‐β‐CD). The host‐guest interactions between Me‐β‐CD and photosensitive monomer (PM) were further investigated by 1HNMR and fluorescence spectroscopy, where the corresponding equilibrium constant was also calculated. Compared with pure PU, the tensile strength and thermal stability of UV‐curable PU films increased evidently. Furthermore, cotton fabrics treated by PU were obtained via soaking method. To further construct a 3D cross‐linked network, the UV‐curable technique was applied by adopting PM with different amounts of the unsaturated bond, which could provide cotton fabrics with different functionalities. The results show that the higher amount of unsaturated bond, the better water repellency which cotton fabrics own. What's more, the water repellency of the waterborne polyurethane fabric obtained by the host‐guest inclusion was larger than that of the physical mixture. Those provide a strategy for synthesizing functional PU based on guest regulation, which can be applied for fabric finishing.

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“…The use of cyclodextrins is verified in diverse industrial products, such as pharmaceuticals [107,111,112], agrochemicals [113][114][115], and foods [116][117][118][119]. In the food area, cyclodextrins are nontoxic and considered GRAS, and thus are used for several purposes [120,121].…”

Section: Cyclodextrinsmentioning

confidence: 99%

β-Cyclodextrins as Encapsulating Agents of Essential Oils

Capelezzo¹,

Mohr²,

Dalcanton³

et al. 2018

Cyclodextrin - A Versatile Ingredient

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Many scientific studies have made advances in the ability to encapsulate natural extracts by cyclodextrins. These studies have addressed the physical and chemical conditions of the encapsulation reactions, employed several types of essential oils and characterized the microcapsules as to their ability to release encapsulated active principles. The essential oils studies with cyclodextrin encapsulation processes have been highly varied. However, the most studied are the essential oils with antimicrobial and antioxidant capacities. The essential antimicrobial and antioxidant oils are easily degraded. In the presence of oxygen, they are oxidized, and at low temperatures, they are volatilized and decomposed. Thus, cyclodextrins are coatings capable of protecting these essential oils from environmental conditions and agents capable of promoting oil degradation, in addition to controlling their release. In this chapter of the book, we review scientific papers that examine the encapsulation of antimicrobial essential oils and antioxidant essential oils with β-cyclodextrins.

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Inclusion complexation of chloropropham with β-cyclodextrin: Preparation, characterization and molecular modeling

Cited by 55 publications

References 28 publications

RESVERATROL INCLUSION COMPLEX WITH Β-Cyclodextrin (RCD): CHARACTERIZATION AND EVALUATION OF TOXICITY IN WISTAR RATS

RESVERATROL INCLUSION COMPLEX WITH Β-Cyclodextrin (RCD): CHARACTERIZATION AND EVALUATION OF TOXICITY IN WISTAR RATS

Preparation, Characterization and Application of Cyclodextrin‐Containing UV‐Curable Waterborne Polyurethane Based on Guest Regulation

β-Cyclodextrins as Encapsulating Agents of Essential Oils

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