Incidental 99mTc MDP uptake in the intestines and intravenous CT contrast

Kim, Soo J; Choi, Joon Young; Lee, Joo H; Hyun, Seung Hyup; Cho, Young S; Moon, Seung Hwan; Choe, Yearn Seong; Lee, Kyung-Han; Kim, Byung‐Tae

doi:10.3413/nukmed-0768-15-09

Cited by 5 publications

(2 citation statements)

References 16 publications

(18 reference statements)

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“…174 A recent report has shown the administration of intravenous iodinated contrast between the injection and imaging of MDP to be related to bowel visualization in a high proportion of patients. 175 Although the mechanism involved in this process is not clear, this observation may be useful in explaining previously cryptic cases of bowel MDP uptake (Fig. 20).…”

Section: Sequestrationmentioning

confidence: 95%

Altered Biodistribution of Radiopharmaceuticals Used in Bone Scintigraphy

Zuckier

Martineau

2015

Seminars in Nuclear Medicine

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Section: Sequestrationmentioning

confidence: 95%

Altered Biodistribution of Radiopharmaceuticals Used in Bone Scintigraphy

Zuckier

Martineau

2015

Seminars in Nuclear Medicine

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“…3). Другим вариантом контраст-индуцированных артефактов является аномальное накопление остеотропных РФП печенью или стенками кишечника при проведении сцинтиграфического исследования на фоне внутривенно введенных гадолиний-или йодсодержащих контрастных веществ [9,10].…”

Section: результатыunclassified

Focal Artefacts in Skeletal Scitigraphy

Mironov

Василенко

Karalkina

et al. 2021

Vestn. rentgenol. radiol.

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Objective: to clarify and systematize the causes that can induce focal artefacts in skeletal scintigraphy with 99mTc-pyrophosphate (PyP), their semiotics, principles and methods of differentiation from bone pathology.Material and methods. Results of skeletal scintigraphy from 1568 patients were analyzed. Scanning in “whole body” mode started in 3 hours after 740 MBq of radiotracer activity intravenous administration, and performed in anterior and posterior projections in continuous table motion mode at rate of 12 cm per minute. Single photon emission computed tomography/computed tomography was additionally performed when necessary.Results. Focal artifacts were detected in 40 patients (2.55%) and were divided into “cold” and “hot” according to the nature of the bone system changes they simulated. “Cold” spots (n = 29) were the result of the shielding effect of metal accessories (n = 10), implants, endoprostheses (n = 18), and barium suspension residues in the large intestine (n = 1). “Hot” spots (n = 11) mimicking metastatic lesion of bone structures were the results of the projection effect of extraosseous uptake of 99mTc-PyP (n = 9) or urinary contamination (n = 2). “Hot” spots in the projection of the upper pole of the kidney (n = 5) could be the result of both calicostasis (n = 3) and injury of the adjacent rib (n = 2). The high uptake of 99mTc-PyP in thyroid nodule (n = 3) simulated a “hot” spot in the lateral part of the cervical vertebra. Abnormal accumulation of 99m Tc-PyP in the nipple-areola areas of the breast was projected onto the posterior segments of the ribs. Urinary contamination imitated focal pathology of the pelvic bones. To differentiate the focal pathology of the ribs and calicostases, the patients were examined in the standing position. The “mask in” program was used to clarify the localization and projection correspondence of “hot” foci.Conclusion. Analysis of focal artefacts formation causes in skeletal scintigraphy contributes to an adequate assessment of the data obtained, allows to choose the necessary method for their diagnosis and to avoid false results of osteoscintigraphy.

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