Incidencia de enterocolitis necrosante en niños prematuros alimentados precozmente

Pérez, Luis; Pradilla, Germán Lauro; Díaz, Gaby; Bayter, Sandra María

doi:10.7705/biomedica.v31i4.397

Cited by 7 publications

(4 citation statements)

References 28 publications

(36 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A total of 2,199 title and abstracts were screened after removing the duplicates, and 102 full texts were retrieved for assessing their eligibility for inclusion. Thirty-nine studies enrolling 6,982 neonates were included in the final synthesis [8, 19‒56] (Table 2). The PRISMA flow is given in online suppl.…”

Section: Resultsmentioning

confidence: 99%

“…None of the RCTs had blinded the intervention to the care providers due to the nature of the intervention. Ten trials had blinded the assessment of NEC [8,19,20,23,35,36,40,45,46,55]. Two trials had a high risk of attri-tion bias [44,52].…”

Section: Risk Of Biasmentioning

confidence: 99%

“…While nineteen studies were classified as having a low risk of bias [8,[19][20][21][22][23][24][25]27,28,31,33,36,37,40,41,45,47,48], nineteen studies were categorised as having a variable risk of bias for random sequence generation and allocation concealment. [26,29,30,32,34,35,38,39,[42][43][44]46,[49][50][51][52][53][54][55] None of the RCTs had blinded the intervention to the care providers due to the nature of the intervention. Ten trials had blinded the assessment of NEC.…”

Section: Risk Of Biasmentioning

confidence: 99%

“…Ten trials had blinded the assessment of NEC. [8,19,20,23,35,36,40,45,46,55] Two trials had a high risk of attrition bias. [44,52] The risk of bias summary and risk of bias graph is given in Supplement figure 3.…”

Section: Risk Of Biasmentioning

confidence: 99%

See 3 more Smart Citations

Enteral Feeding Strategies in Preterm Neonates ≤32 weeks Gestational Age: A Systematic Review and Network Meta-Analysis

et al. 2021

View full text Add to dashboard Cite

Introduction: Critical aspects of time of feed initiation, advancement, and volume of feed increment in preterm neonates remain largely unanswered. Methods: Medline , Embase, CENTRAL and CINAHL were searched from inception until 25th September 2020. Network meta-analysis with the Bayesian approach was used. Randomized controlled trials (RCTs) evaluating preterm neonates ≤32 weeks were included. Feeding regimens were divided based on the following categories: initiation day: early (<72 h), moderately early (72 h–7 days), and late (>7 days); advancement day: early (<72 h), moderately early (72 h–7 days), and late (>7 days); increment volume: small volume (SV) (<20 mL/kg/day), moderate volume (MoV) (20–< 30 mL/kg/day), and large volume (≥30 mL/kg/day); and full enteral feeding from the first day. Sixteen regimens were evaluated. Combined outcome of necrotizing enterocolitis (NEC) stage ≥ II or mortality before discharge was the primary outcome. Results: A total of 39 studies enrolled around 6,982 neonates. Early initiation (EI) with moderately early or late advancement using MoV increment enteral feeding regimens appeared to be most efficacious in decreasing the risk of NEC or mortality when compared to EI and early advancement with SV increment (risk ratio [95% credible interval]: 0.39 [0.12, 0.95]; 0.34 [0.10, 0.86]) (GRADE–very low). Conclusions: Early initiated, moderately early, or late advanced with MoV increment feeding regimens might be most appropriate in decreasing the risk of NEC stage ≥II or mortality. In view of the certainty of evidence being very low, adequately powered RCTs evaluating these 2 strategies are warranted.

show abstract

Section: Resultsmentioning

confidence: 99%