Incidence, Predictive Factors, and Prognostic Significance of Supraventricular Tachyarrhythmias in Congestive Heart Failure

Atrial fibrillation in patients hospitalized for congestive heart failure: The same prognostic influence independently of left ventricular systolic function?

“…The results of this study agree with earlier reports in finding that atrial fibrillation increases the risk of death among CHF patients with deteriorated systolic function independently of other variables considered [5,8,12,13]. Although we have no information on the causes of death of the deceased patients in this study, it seems possible that for those with deteriorated systolic function, atrial fibrillation may increase the risk of sudden death or stroke, and/or contribute to the development of refractory heart failure.…”

Atrial Fibrillation and Risk of Clinical Events in Chronic Heart Failure With and Without Left Ventricular Systolic Dysfunction

“…The DIG trial included 988 patients with LVEF Ͼ0.45 and clinical signs of heart failure in an ancillary study, and these patients were analyzed for incidence of supraventricular tachycardia together with patients in the main trial. The development of supraventricular tachycardia during the study was independently associated with a higher risk of mortality and stroke regardless of baseline EF (28).…”

Age-Dependent Prognostic Significance of Atrial Fibrillation in Outpatients with Chronic Heart Failure: Data from the Italian Network on Congestive Heart Failure Registry

“…Two large trials [30,31] with a total of 14,000 patients reported that the all-cause mortality rate was significantly higher in the presence of AF. Middlekauff et al [32] demonstrated the negative prognostic role of AF in patients with HF, even though, interestingly, in this study the authors underlined that AF lost its predictive power in patients with a worse hemodynamic profile.…”