Incidence of the acute renal failure in the intensive care unit at the General Hospital of Mexico: Risk factors and associated morbidity and mortality

Herrera-Méndez, J.; Sánchez-Velázquez, Luis David; González-Chávez, Antonio; Rodríguez-Terán, Gerardo

doi:10.1016/j.hgmx.2015.04.005

Cited by 2 publications

(1 citation statement)

References 24 publications

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“…In the presence of sepsis, the reported incidence of AKI was greater than 70%, and mortality rate reached 80%, higher in patients undergoing RRT, 1,10,11,14,17,24,34,36,37,[39][40][41][42][43] Sepsis was also an independent factor that increased the length of stay of individuals in ICUs. 11 The pathophysiological dynamics of the interaction between sepsis and AKI are not fully understood, and the association between sepsis and AKI in ICU patients can cause vascular, glomerular, tubular, and interstitial damage in the kidneys.…”

Section: Discussionmentioning

confidence: 99%

An epidemiologic overview of acute kidney injury in intensive care units

Santos

Carvalho

Peres

et al. 2019

Rev. Assoc. Med. Bras.

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SUMMARY INTRODUCTION Acute kidney injury (AKI) is a frequent event among critically ill patients hospitalized in intensive care units (ICU) and represents a global public health problem, being imperative an interdisciplinary approach. OBJECTIV To investigate, through literature review, the AKI epidemiology in ICUs. METHODS: Online research in Medline, Scientific Electronic Library Online, and Latin American and Caribbean Literature in Health Sciences databases, with analysis of the most relevant 47 studies published between 2010 and 2017. RESULTS Data of the 67,033 patients from more than 300 ICUs from different regions of the world were analyzed. The overall incidence of AKI ranged from 2.5% to 92.2%, and the mortality from 5% to 80%. The length of ICU stay ranged from five to twenty-one days, and the need for renal replacement therapy from 0.8% to 59.2%. AKI patients had substantially higher mortality rates and longer hospital stays than patients without AKI. CONCLUSION AKI incidence presented high variability among the studies. One of the reasons for that were the different criteria used to define the cases. Availability of local resources, renal replacement therapy needs, serum creatinine at ICU admission, volume overload, and sepsis, among others, influence mortality rates in AKI patients.

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Section: Discussionmentioning

confidence: 99%

An epidemiologic overview of acute kidney injury in intensive care units

Santos

Carvalho

Peres

et al. 2019

Rev. Assoc. Med. Bras.

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Prevention and Early Detection of Acute Kidney Injury in Intensive Care Unit: A Systematic Review

Jamaludin

Nurumal

Hasan

et al. 2022

Int J Care Scholars

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Acute Kidney Injury (AKI) is often associated with Intensive Care Unit (ICU) admission and results in a higher mortality rate around the world. The AKI cases have been rising for the past decade alongside the mortality rate. Literature has shown that early detection helps in overcoming the problem. This systematic review aims to identify the identify the relevant literature and to summarize the prevention and early detection of AKI in the ICU setting to reduce the morbidity and mortality rate of patients. A total of 20 articles identified in this review. This systematic review also is in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant studies were identified based on the inclusion criteria with language filters but were limited to articles published from the year 2010 to 2020. Two reviewers independently conducted the quality assessment, data extraction, and analysis on all included studies. The result indicates there are several biomarkers which are helpful in detecting AKI such as Neutrophil Gelatinase-Associated Lipocalin (NGAL), Interleukin-18 (IL-18), Tissue Inhibitor of Metalloproteinase 2 (TIMP-2), Insulin-Like Growth Factor Binding Protein 7 (IGFBP-7), Protein C (PC), and soluble thrombomodulin (sTM). This review also addressed nursing responsibilities for early detection and prevention of AKI. Thus, severe cases of AKI and mortality cases associated with AKI can be minimized with better predictive and proper management.

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Incidence of the acute renal failure in the intensive care unit at the General Hospital of Mexico: Risk factors and associated morbidity and mortality

Cited by 2 publications

References 24 publications

An epidemiologic overview of acute kidney injury in intensive care units

An epidemiologic overview of acute kidney injury in intensive care units

Prevention and Early Detection of Acute Kidney Injury in Intensive Care Unit: A Systematic Review

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