2018
DOI: 10.1111/ijd.14215
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Incidence of squamous cell carcinoma in oral lichen planus: a 25-year population-based study

Abstract: Patients with OLP, particularly the erosive type, have an increased incidence of OSCC development and should be monitored closely.

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Cited by 33 publications
(31 citation statements)
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“…After title/abstract screening, 4324 papers were selected for abstract evaluation. Of these, 92 studies were included in the final analysis . Fourty‐six reports were on LP, 5 on OLL, 28 on LE, 8 on OE, 4 on OSF, and 11 on PVL (all the studies taken for every subgroup sum up to a figure higher than 92 because some studies focused on more than one OPMD).…”
Section: Resultsmentioning
confidence: 99%
“…After title/abstract screening, 4324 papers were selected for abstract evaluation. Of these, 92 studies were included in the final analysis . Fourty‐six reports were on LP, 5 on OLL, 28 on LE, 8 on OE, 4 on OSF, and 11 on PVL (all the studies taken for every subgroup sum up to a figure higher than 92 because some studies focused on more than one OPMD).…”
Section: Resultsmentioning
confidence: 99%
“…La Tabla 3 (2,7,(9)(10)(11)(12)(13)(14)(15) En los estudios en los que se estudiaron también los casos de RL y se analizó su rango de malignización (7,11) observamos una mayor incidencia de malignización (2.1% (7) y 4.4% (11) ).…”
Section: Resultsunclassified
“…Por otro lado, Van der Meij et al (7) hicieron un seguimiento de 5 años a un total de 192 pacientes y no encontraron ninguna malignización de lesiones de LPO; sí obtuvieron, en cambio, un 2.1% de casos de malignización de RL. De manera similar, Casparis et al (9) , encontraron también diferencias entre RL y LPO, con porcentajes menores para liquen plano oral (1.2%) que para las reacciones liquenoides (4.4%). Cortés et al (6) concluyen en su revisión que hay una diferencia clara en el pronóstico de las lesiones y, coincidiendo con lo anteriormente expuesto, las RL presentan un mayor índice de malignizaciones que las lesiones de LPO y es por este motivo que se propone la nueva clasificación para las lesiones de LPO.…”
Section: Mucosa Bucal (N) Encía (N) Lengua (N) Paladar (N) Labio (N)unclassified
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“…In a large study of 722 patients, Eisen et al identified six patients (0.8%) who went on to develop SCCA at a site previously known to have erosive or erythematous OLP, two of which developed tongue tumors (at 44 and 49 years of age) . In a population‐based retrospective study of 303 patients with OLP in Minnesota over a 25 year period, Laniosz et al found that patients with OLP were 4.8 times more likely to develop SCCA than their matched referents (seven patients developed SCCA with an average age at diagnosis of 65.8 years) . A recent meta‐analysis of 33 studies with a total of 12 838 OLP patients reported a malignant transformation rate of only 0.44%, suggesting that previously reported rates may be exaggerated to some degree.…”
Section: Role Of Immune Evasion In Tumor Development and Progressionmentioning
confidence: 99%