Incidence of Psychogenic Seizures in Adults: A Population‐Based Study in Iceland

Sigurdardottir, Katrin Ruth; Ólafsson, Elías

doi:10.1111/j.1528-1157.1998.tb01161.x

Cited by 211 publications

(130 citation statements)

References 24 publications

(25 reference statements)

Supporting

Mentioning

112

Contrasting

Unclassified

Order By: Relevance

“…Although previous studies have reported a high prevalence (5%-50%) of ES in PNES patients (PNES/ES) (Sigurdardottir and Olafsson, 1998;Benbadis et al, 2001;Martin et al, 2003), few authors investigated PNES and PNES/ES patients separately to determine the possible influence of this comorbidity on psychological and clinical aspects (Devinsky et al, 1996;Owczarek and Jederzejczak, 2001;Reuber et al, 2002;Kuyk et al, 2003;Galimberti et al, 2003).…”

mentioning

confidence: 99%

“…Video-EEG recording of a typical episode is considered the "gold standard" for the diagnosis of PNES, because diagnostic clinical criteria are not available (Reuber and Elger, 2003). A previous study reported an incidence of PNES of 1.5 per 100,000 per year (equivalent to approximately 4% of all epilepsy cases) (Sigurdardottir and Olafsson, 1998). This figure probably does not reflect accurately the true extent of PNES, because this condition is often underestimated and may be misdiagnosed as epileptic seizures (ES).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Video‐EEG Study of Psychogenic Nonepileptic Seizures: Differential Characteristics in Patients with and without Epilepsy

Mari

Bonaventura

Vanacore³

et al. 2006

Epilepsia

View full text Add to dashboard Cite

Summary:Purpose: Psychogenic nonepileptic seizures (PNES) are episodes that may resemble epileptic seizures (ES) but are not associated with abnormal electrical discharges in the brain. Video-EEG recording of a typical episode is considered the best diagnostic tool available. PNES are, however, also documented in patients with epilepsy (PNES/ES). The purpose of this study was to assess this comorbid population, focusing on the differences between patients with PNES/ES and patients with PNES alone.Methods: We reviewed 110 PNES episodes, occurring spontaneously or induced by means of suggestion techniques, recorded in our video-EEG laboratory over a period of eight years. We identified two subgroups of patients, consisting of 85 PNES cases and 25 PNES/ES cases, and assessed any differences in their characteristics by reviewing a number of variables (age, sex, clinical features, antiepileptic therapy, age of onset, time to diagnosis, pathological history, and length of follow-up).Results: The comparison between the two subgroups revealed that PNES/ES patients displayed some statistically significant differences when compared with PNES alone patients, i.e., younger age, a higher percentage of spontaneously activated events, a shorter disease duration, a longer time to PNES diagnosis, and a lower percentage lost at follow-up.Conclusions: This study confirms that PNES is a common, though probably underestimated, occurrence in epilepsy services. Our results shed light on some different characteristics between PNES and PNES/ES patients.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

Video‐EEG Study of Psychogenic Nonepileptic Seizures: Differential Characteristics in Patients with and without Epilepsy

Mari

Bonaventura

Vanacore³

et al. 2006

Epilepsia

View full text Add to dashboard Cite

show abstract

“…Other studies evaluated the association between PNESs and psychological or sexual trauma or other psychiatric comorbities (30,31), outcome after the diagnosis of PNESs (13,(24)(25)(26), or the incidence of PNESs (20,21). Only two studies evaluated HRQOL in patients with PNESs (14,32).…”

mentioning

confidence: 99%

“…The prevalence of PNESs is ∼2-33/100,000 of the general population and between 10 and 58% of the patients with intractable epilepsy seen in specialized epilepsy centers (15,19). The incidence of definite PNESs is 1.4-3.03/100,000 per year (20,21); thus the number of patients with PNESs could be as high as 300,000 to 400,000 (22). Because PNESs are resistant to the standard medical therapies used for the treatment of ESs, the financial cost of their treatment may be very high (23).…”

mentioning

confidence: 99%

Quality of Life in Psychogenic Nonepileptic Seizures

Szaflarski¹,

Hughes²,

et al. 2003

View full text Add to dashboard Cite

Summary:Purpose: Psychogenic nonepileptic seizures (PNESs) are events that alter or seem to alter the neurologic function and, in their appearance, resemble epileptic seizures (ESs). In patients with ESs the psychological and medical aspects of epilepsy greatly influence the health-related quality of life (HRQOL). The relation between these factors and PNESs is not well established. In this study, we compared HRQOL in patients with PNESs with that of patients with ESs.Methods: We evaluated 105 patients admitted to the Epilepsy Monitoring Unit of University Hospital between January 20, 2001, and January 20, 2002. Only patients with the definite diagnosis of ESs or PNESs were analyzed (n ‫ס‬ 85). Patients completed an epilepsy-specific quality-of-life instrument (QOLIE-89), the Profile of Mood States (POMS), and Adverse Events Profile (AEP). We used t tests and regression analyses to contrast HRQOL in PNESs and ESs and to elucidate the main factors associated with HRQOL in patients with PNESs.Results: In our sample, 45 patients had PNESs, and 40 hadESs. The overall HRQOL and scores on 13 of 19 QOLIE-89 subscales were significantly lower (i.e., worse) in PNES than in ES patients. AEP and scores on five of six POMS subscales also were worse in PNES patients than in ES patients. PNES versus ES diagnosis, POMS depression/dejection, and AEP were significant predictors of HRQOL, jointly explaining 65% variation in HRQOL. The lower HRQOL in PNESs versus ESs was in part explained by depression and AEP.Conclusions: Patients with PNESs have a lower HRQOL and worse mood problems than do patients with ESs. This disadvantage is primarily due to depression and medication side effects, although these factors influence QOL in much the same way in PNES and ES patients. These baseline HRQOL data on patients with PNESs can be used to evaluate the effects of treatment in this patient population.

show abstract

“…100 000 főre eső incidenciája 1,4-4,9 eset évente, de a diagnosztikai nehézségek miatt a valós arány ennél minden bizonnyal magasabb [10,11]. Benbadis és Allen-Hauser becslései szerint a 100 000 főre eső prevalencia 2-33 eset évente [12].…”

Section: Epidemiológiaunclassified

Pszichogén nem epilepsziás rosszullétek a klinikai gyakorlatban

Szita

Hidasi

2016

Orvosi Hetilap

View full text Add to dashboard Cite

A pszichogén, nem epilepsziás roham a pszichiátria és neurológia határterületén lévő, nehezen behatárolható tünet-együttes, amely tünetmintázatában hasonlít az epilepsziára, de azt nem epilepsziás aktivitás váltja ki. Jellemzően fiatal felnőttkorban alakul ki, a betegek körében a nők aránya jóval magasabb. A pszichogén, nem epilepsziás roham diagnosztikája elsősorban video-elektroencefalográfiás vizsgálattal történhet, amely az esetek 90%-ában a helyes diagnózis megállapításához vezethet. A kórképet mégis gyakran diagnosztizálják tévesen epilepsziának, és kezelik évekig ennek megfelelően, ami a betegekre és az egészségügyi ellátórendszerre egyaránt nagy terhet ró. A kórkép etiológiájában -az anamnézisben szereplő traumatikus életesemények gyakorisága miatt -kiemelt szerepet tulajdonítanak a pszichológiai faktoroknak. Emellett a pszichogén nem epilepsziás roham kialakulásában neurobiológiai tényezők is köz-rejátszanak, amelyre a betegek egy részénél talált kognitív, strukturális és funkcionális agyi eltérések utalnak. A kezelés pszichoszociális -elsősorban kognitív viselkedésterápiás -intervenciókat és kiegészítő farmakoterápiát foglal magába. A tanulmányban a szerzők a pszichogén nem epilepsziás roham tünettanával, diagnosztikájával, etiológiájával és kezelésével kapcsolatos irodalmat és az újabb kutatási eredményeket tekintik át. Orv. Hetil., 2016, 157(20), 767-775. Kulcsszavak: pszichogén nem epilepsziás roham, video-EEG, szemiológia, etiológia, kezelés Psychogenic nonepileptic seizures: overview and implications for practicePsychogenic nonepileptic seizures are enigmatic disorders at the interface of neurology and psychiatry. Seizures resemble epileptic seizures but are not associated with electrical discharges in the brain. Symptoms typically start in early adulthood and women are far more affected than men. Video-EEG is widely considered to be the gold standard for diagnosis. Still psychogenic nonepileptic seizures are often misdiagnosed and treated as epilepsy for years that is burdensome to patients and costly to the healthcare system. Patients having psychogenic nonepileptic seizures show a high prevalence of traumatic life events, therefore, psychosocial factors are thought to play an important role in the etiology. Neurobiological factors may also contribute to the development of seizures as a subgroup of patients are characterized by cognitive impairment and subtle structural and functional brain abnormalities. Treatment includes psychotherapeutic procedures, particularly cognitive behavioral therapy and additional pharmacological interventions. This article presents an overview of the clinical context, diagnosis, etiology and treatment of psychogenic nonepileptic seizures. Rövidítések CBT = kognitív viselkedésterápia; EMG = elektromiográfia; MMPI = Minnesota Multiphasic Personality Inventory; PNER = pszichogén nem epilepsziás roham; PTSD = poszttraumás stressz zavar; SISCOM = Subtraction Ictal SPECT Co-registered to MRI; SSRI = (selective serotonin reuptake inhibitor) szelektív szerotonin-visszavétel...

show abstract

Incidence of Psychogenic Seizures in Adults: A Population‐Based Study in Iceland

Cited by 211 publications

References 24 publications

Video‐EEG Study of Psychogenic Nonepileptic Seizures: Differential Characteristics in Patients with and without Epilepsy

Video‐EEG Study of Psychogenic Nonepileptic Seizures: Differential Characteristics in Patients with and without Epilepsy

Quality of Life in Psychogenic Nonepileptic Seizures

Pszichogén nem epilepsziás rosszullétek a klinikai gyakorlatban

Contact Info

Product

Resources

About