Incidence of minor and major amputations after pancreas/kidney transplantation

Woeste, Guido; Wullstein, C.; Pridöhl, Olaf; Lübke, P; Schwarz, R; Kohlhaw, K.; Bechstein, Wolf O.

doi:10.1111/j.1432-2277.2003.tb00274.x

Cited by 23 publications

(24 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is in contrast with the baseline characteristics, where we found the opposite: more often a history of amputations in the preemptive group. These data confirm previous studies who have indicated that the amputation rate did not drop after a SPKT (11,12).…”

Section: Discussionsupporting

confidence: 95%

Preemptive versus Nonpreemptive Simultaneous Pancreas-Kidney Transplantation: A Single-Center, Long-Term, Follow-up Study

et al. 2006

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 95%

Preemptive versus Nonpreemptive Simultaneous Pancreas-Kidney Transplantation: A Single-Center, Long-Term, Follow-up Study

et al. 2006

View full text Add to dashboard Cite

show abstract

“…In another study, the incidence of PAD (amputations or revascularizations) was three (8%) of 36 among kidney-pancreas recipients and 10 (11%) of 88 among kidney-only transplant recipients after a median of 45 mo of follow-up (8). Similarly, Woeste et al (9) reported that 19 (9.5%) of 200 kidney-pancreas recipients who received a transplant between 1995 and 2001 underwent amputations an average of 18.7 mo after transplantation. Therefore, the incidence of PAD after kidney transplantation among patients with and without diabetes in these single-center studies is comparable to that found in our study.…”

Section: Discussionmentioning

confidence: 92%

Peripheral Arterial Disease and Renal Transplantation

Snyder

Kasiske

Maclean

2006

Journal of the American Society of Nephrology

View full text Add to dashboard Cite

It was hypothesized that peripheral arterial disease (PAD) is less frequent after kidney transplantation than among comparable patients who are on the deceased-donor waiting list. The cumulative incidences and risk factors for PAD were compared among 43,427 adult transplant recipients and 53,309 adults who were placed on the renal transplant waiting list between 1995 and 2003. All patients had Medicare primary insurance coverage, and Medicare claims were used to identify PAD. For patients with diabetes, the 3-yr cumulative incidence of de novo PAD was 24% on the waiting list versus 20% after transplantation. For patients without diabetes, the 3-yr cumulative incidence was 9% on the waiting list versus 5% after transplantation. The adjusted relative risk (RR) for PAD among patients without diabetes was 0.73 (95% confidence interval [CI] 0.66 to 0.80; P < 0.0001) in the transplant population versus the waiting list population, whereas among patients with diabetes, it was 0.88 (95% CI 0.82 to 0.96; P ‫؍‬ 0.0024). A diagnosis of PAD on the waiting list was associated with an almost three-fold increase in the RR for death for patients without diabetes (2.98; 95% CI 2.71 to 3.27; P < 0.0001) and with diabetes (2.92; 95% CI 2.71 to 3.15; P < 0.0001). After transplantation, de novo PAD increased the RR for death almost two-fold in patients without diabetes (1.92; 95% CI 1.63 to 2.26; P < 0.0001) and with diabetes (1.83; 95% CI 1.58 to 2.12; P < 0.0001). The incidence of PAD is higher on the waiting list than after transplantation and is associated with an increased risk for death among patients with and without diabetes.

show abstract

“…Woeste et al (15) in a retrospective single-center study of 210 kidney-pancreas transplant recipients found that the incidence of amputation was 9.8% and the average time to amputation was 18.7 months. This is in sharp contrast to our study in which the incidence of amputation was 1.4% and median time from transplantation to amputation was 14 months; the higher incidence in the Woeste et al study may be secondary to increased incidence of diabetes in that cohort.…”

Section: Discussionmentioning

confidence: 97%