Incidence of Maternal Rh Immunization by ABO Compatible and Incompatible Pregnancies

Rh Prevention: A Report and Analysis of a National Programme

“…and 0*13%, respectively. The pattern of immunization thus seems to be different from that seen in untreated control series, where approximately half of the immunized mothers form antibodies after the first observed pregnancy, as reported by Ascari, Levine, and Pollack (1969) and Woodrow and Donohoe (1968), or calculated indirectly from the clinical series. With the very low failure rate (0-13 %) in the post-delivery controls in the present series, the difference was more distinct than in other series reported from elsewhere (Schneider, 1971).…”

Prevention of Rh-haemolytic Disease: Final Results of the "High-risk" Clinical Trial: A COMBINED STUDY FROM CENTRES IN ENGLAND AND BALTIMORE

“…Mention has already been made of antigammaglobulin antibodies, and Ascari et al (1969), thinking along different lines, speculated that gammaglobulin used for rubella prophylaxis might contain a small amount of IgG anti-D, and that this might have an enhancing effect in the sense, presumably, that any Rh-positive fetal cells entering the maternal circulation at the time of the injection might be more likely to immunize the mother. However, various batches of pooled gammaglobulin used for general prophylactic purposes have since been examined (K. L. G. Goldsmith, personal communication, 1970) and no definite evidence of anti-D has been found in any of them.…”

Rapid Clearance of Rh Positive Rlood During Experimental Rh Immunisation

“…Some of the reported failures of prophylactic therapy may come into this category. However, the very high rate of success of the preventive treatment [Clarke, 1968;Ascari et al, 1969] implies that it cannot be a very common event.…”