Incidence of interface fluid syndrome after laser in situ keratomileusis in Egyptian patients

Abstract

PurposeTo determine the incidence of interface fluid syndrome (IFS) secondary to steroid-induced elevation of intraocular pressure (IOP) following laser in situ keratomileusis (LASIK) in myopic Egyptian patients.MethodsThis retrospective case series study was conducted at El-Gowhara Private Eye Center. The medical records of 1,807 patients (3,489 eyes), who underwent LASIK to correct myopia from April 2012 to December 2015 were included. The patients were operated on and reviewed by one surgeon (AAG) for IFS after LASIK associated with elevation of IOP (as compared to preoperative values).ResultsThis paper reports the incidence of 2.9% (54 patients) (102 eyes) of IFS induced by increased IOP after LASIK in Egyptian patients. The medical records of 1,807 patients (3,489 eyes) with mean age ± standard deviation (SD) 26.4±2.7 years, who presented with mean myopia ± SD −4.50±1.3 D, mean astigmatism ± SD −1.43±0.8, mean IOP ± SD 15.2±1.2 mmHg, and mean central corneal thickness ± SD 549±25.6 μm, were included. The preoperative anterior and posterior segments, corneal topography, and Schirmer’s test were unremarkable.ConclusionLimiting topical steroids and routinely measuring the IOP post-LASIK are necessary steps to prevent IFS, especially in case of myopia. A high index of suspicion is required to make a diagnosis. High-resolution optical coherence tomography is helpful to confirm the diagnosis.

Interface Fluid Syndrome (IFS) following Toxic Anterior Segment Syndrome (TASS): not related to high intraocular pressure but to endothelial failure

“…Elevated IOP should be thus present in around this percentage of the patients undergoing LASIK or those with a history of LASIK undergoing another intraocular procedure 27 . Recently Gab-Alla in Egypt in LASIK patients who received a postoperative regimen of topical dexamethasone for 1 month found that 2,9% presented IFS 28 …”

“… 27 Recently Gab-Alla in Egypt in LASIK patients who received a postoperative regimen of topical dexamethasone for 1 month found that 2,9% presented IFS. 28 …”

Evaluate the Prevalence, Natural Course, and Final Visual Acuity in Patients with Stages III or IV of Diffuse Lamellar Keratitis Following Laser in Situ Keratomileusis

“…Increased intraocular pressure (IOP) following surgery can create a clinical picture similar to DLK (false DLK) 9 . Therefore, IOP control is necessary in patients with suspected DLK 10 .…”

Interface fluid syndrome secondary to endothelial failure due to toxic anterior segment syndrome after cataract surgery

“…1 It has been mainly related to increased intraocular pressure (IOP), mostly due to the use of corticosteroids after surgery. [1][2][3] It may also be a result of endothelial decompensation caused by several pathologies, which may occur years after surgery. [4][5][6][7] Toxic anterior segment syndrome (TASS) is a sterile anterior segment inflammation within 48 h after cataract surgery, may cause endothelial cell destruction, which was reported in 0.22%-0.80% of patients.…”