Incidence of fundic gland polyps in patients without familial adenomatous polyposis

Giant sporadic fundic gland polyp: Endoscopic and endosonographic features and management

“…They are found in up to 1.9% of the general population, 5% of patients presenting for upper gastrointestinal endoscopy, 84% of patients with familial adenomatous polyposis (FAP), and in 93% of those with attenuated-FAP (AFAP) [1,2] . FGPs are usually asymptomatic, though some patients may complain of dyspepsia.…”

Sporadic Fundic Gland Polyps With Low-Grade Dysplasia: A Large Case Series Evaluating Pathologic and Immunohistochemical Findings and Clinical Behavior

“…3,4 They are slightly more common in women than in men, and their occurrence has been associated with prolonged use of proton pump inhibitors (PPIs). 3,4 In sporadic FGPs, low-grade epithelial dysplasia has been described, but its prevalence is extremely rare (approximately 1%). 5 Syndromic FGPs arise in patients with FAP, have been reported in 12.5% to 84% of patients with FAP, occur in a younger age group, and equally affect men and women.…”

“…5 Syndromic FGPs arise in patients with FAP, have been reported in 12.5% to 84% of patients with FAP, occur in a younger age group, and equally affect men and women. 4,[6][7][8][9][10][11][12][13] Epithelial dysplasia is more common Upon completion of this activity you will be able to:• describe the features of sporadic fundic gland polyps with low-grade dysplasia in terms of the incidence of these polyps, patient characteristics, and pathologic and immunohistochemical findings.• compare and differentiate between fundic gland polyps with low-grade dysplasia in the sporadic and syndromic setting.The ASCP is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The ASCP designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit ™ per article.…”

Fundic Gland Polyps in Familial Adenomatous Polyposis

“…1 FGPs are reported to occur in 12.5 to 84% of patients with FAP, [2][3][4][5][6][7][8][9][10][11][12][13] whereas sporadic FGPs are identified in 0.8 to 1.9% of non-FAP patients undergoing upper gastrointestinal endoscopy. 14,15 In addition to increased prevalence in patients with FAP, FAPassociated FGPs tend to be more numerous, occur at a younger age, and have a more equal gender distribution than sporadic FGPs. 14 -17 Histopathologically, FGPs are characterized by cystically dilated and irregularly budded fundic glands in a background of otherwise normal gastric mucosa.…”