Incidence of early-onset dementia in Mar del Plata

Abraham, Marina Sanchez; Scharovsky, Diana; Romano, Lucas Martín; Ayala, Miguel Ángel; Alemán, Alberto; Sottano, Eugenia; Etchepareborda, Ignacio; Machado, Cláudia; García, María Inés; Gonorazky, Sergio Eduardo

doi:10.1016/j.nrleng.2013.10.020

Cited by 5 publications

(11 citation statements)

References 29 publications

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“…13 In this study, which used a relatively broad population age range of 21-64 years, a higher incidence rate was still reported than in the present study. 13 However, it should be noted that the Argentinian study was based on only one health service attending a closed population of 17 614 in a small geographic area and used only 14 cases diagnosed as EOD as the numerator. Small-scale case sampling from a small population such as this will probably result in selection bias and a large confidence interval.…”

Section: Discussioncontrasting

confidence: 63%

“…reported 13.4/100 000 person‐years in the population aged 30–64 years in Spain 12 ; Sanchez Abraham et al . reported 5.8/100 000 person‐years in the population aged 21–64 years in Argentina 13 ; and Kvello‐Alme et al . reported 14.8/100 000 person‐years in the population aged 30–64 years in Norway.…”

Section: Discussionmentioning

confidence: 99%

“…However, it is expensive and exceedingly difficult to conduct studies that address both of these issues. As such, previous studies of the incidence of EOD have used a clinic‐based rather than a community‐based approach, in which the clinical registry or clinical records were used as a data source to identify cases within a geographically defined area 4–14 …”

Section: Introductionmentioning

confidence: 99%

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Incidence and distribution of subtypes of early‐onset dementia in Japan: A nationwide analysis based on annual performance reports of the Medical Centers for Dementia

Edahiro

Miyamae

Taga

et al. 2020

Geriatrics Gerontology Int

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Investigating the incidence rate of early-onset dementia is challenging. We explored the incidence rate of early-onset dementia in Japan using annual performance reports from the Medical Centers for Dementia. Methods: Medical Centers for Dementia are specialized health services for dementia established as part of Japan's national health program. There are 440 such centers nationwide as of 2018. Using the annual performance reports of these centers, we calculated the number of newly diagnosed cases of early-onset dementia or late-onset dementia from April 1, 2018 to March 31, 2019, and the composition ratio by diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. The annual incidence rate of early-onset dementia was estimated using the number of cases as the numerator and the national population aged 18-64 years as the denominator. Results: In total, 1733 of cases were diagnosed with early-onset dementia, of which 52.1% were diagnosed as major neurocognitive disorder due to Alzheimer's disease, 8.9% major frontotemporal neurocognitive disorder, 8.8% major vascular neurocognitive disorder, 7.1% substance/medication-induced major neurocognitive disorder, 6.5% major neurocognitive disorder with Lewy bodies and 3.9% major neurocognitive disorder due to another medical condition. The annual incidence rate of early-onset dementia was estimated to be 2.47/100 000 person-years. Conclusions: This study provides the first nationwide estimate of the incidence rate of early-onset dementia in Japan and suggests that Medical Centers for Dementia are important resources for the epidemiological monitoring of early-onset dementia nationwide.

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Section: Discussioncontrasting

confidence: 63%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Incidence and distribution of subtypes of early‐onset dementia in Japan: A nationwide analysis based on annual performance reports of the Medical Centers for Dementia

Edahiro

Miyamae

Taga

et al. 2020

Geriatrics Gerontology Int

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“…Even outside Scandinavia, the number of studies on this topic is remarkably low and has shown varying incidence rates of YOD. In the UK, Mercy et al found rates of 11.5 cases per 100,000 person-years for the age range 45-64, while in Argentina, Abraham Sanchez et al found 11 cases per 100,000 in the age range 21-64 [6,7]. In Spain, Garre-Olmo et al reported incidence rates of 13.4 in the age category 30-64 years [8].…”

Section: Introductionmentioning

confidence: 99%

Incidence of Young Onset Dementia in Central Norway: A Population-Based Study

Kvello-Alme

Bråthen

White

et al. 2020

JAD

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Background: The epidemiology of young onset dementia is little researched compared to late onset dementia. Information on incidence rates is vital for medical professionals, and for government planning purposes. Objective: To determine the incidence of young onset dementia in a defined catchment area of central Norway. Methods: The target area was Trøndelag county in central Norway with a total population of 449,796 inhabitants per January 1, 2016. We applied multiple case ascertainment strategies with sources from both primary and secondary healthcare facilities. Included patients received a diagnosis of dementia according to DSM-IV in the ages 30 to 64 years during the years 2015-2017. Subtypes of dementia were diagnosed according to standardized criteria. Incidence rates for dementia and Alzheimer's disease with dementia were calculated according to age and sex. Results: A total of 89 incident cases were included. Incidence rates for dementia were 14.8 and 25.0 per 100,000 person-years for the age range 30-64 and 45-64, respectively. Corresponding incidence rates for Alzheimer's disease were 6.7 and 11.8. Alzheimer's disease represented half of all dementias. A majority of patients above the age of 50 had neurodegenerative disease, whereas non-degenerative disorders were more prevalent in younger patients. Conclusion: Young onset dementia is a significant contributor to the overall occurrence of dementia in central Norway, and Alzheimer's disease is by far the most common diagnosis.

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“…Variability results from differences between case mix (see Table 3), and in the sampling methods (for example, see the differences in sample age ranges shown in Table 2). The incidence of all-cause YOD, based on the three studies conducted to date, is 11-13.4 per 100,000 17-19 .…”

Section: Methodsmentioning

confidence: 99%

Young-Onset Dementia Epidemiology Applied to Neuropsychiatry Practice

Devineni

Onyike

2015

Psychiatric Clinics of North America

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Synopsis There is epidemiological evidence that a substantial number of adults suffer YOD. The diversity of types and syndromes makes recognition and diagnosis difficult. An algorithmic approach to interpreting clinical data, informed by clinical epidemiology, integrates data pertaining to defining syndromes, and their chronology and tempo, family history, and other neuropsychiatric features and neurological signs, to reach a preliminary diagnosis and direct diagnostic tests and their interpretation. Screening for YOD in the psychiatric context is a rational process in which vigilance is combined with careful searches for ‘red flags’ that signal a neurodegenerative etiology.

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Incidence of early-onset dementia in Mar del Plata

Cited by 5 publications

References 29 publications

Incidence and distribution of subtypes of early‐onset dementia in Japan: A nationwide analysis based on annual performance reports of the Medical Centers for Dementia

Incidence and distribution of subtypes of early‐onset dementia in Japan: A nationwide analysis based on annual performance reports of the Medical Centers for Dementia

Incidence of Young Onset Dementia in Central Norway: A Population-Based Study

Young-Onset Dementia Epidemiology Applied to Neuropsychiatry Practice

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