Incidence of Congenital Spinal Abnormalities Among Pediatric Patients and Their Association With Scoliosis and Systemic Anomalies

Passias, Peter G.; Poorman, Gregory W.; Jalai, Cyrus M.; Diebo, Bassel G.; Vira, Shaleen; Horn, Samantha R.; Baker, Joseph F.; Shenoy, Kartik; Hasan, Saqib; Buza, John A.; Bronson, Wesley H.; Paul, Justin C.; Kaye, I. David; Foster, Norah; Cassilly, Ryan T.; Oren, Jonathan H.; Moskovich, Ronald; Line, Breton; Oh, Cheongeun; Bess, Shay; Lafage, Virginie; Errico, Thomas J.

doi:10.1097/bpo.0000000000001066

Cited by 44 publications

(38 citation statements)

References 28 publications

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“…Additionally, Passias et al, using data from the Healthcare Cost and Utilization Project's Kids Inpatient Database (KID) in the United States, reported that the incidences of the congenital spinal abnormalities, hemivertebra and the absence of vertebra, were 9.1 and 1.2 per 100,000 persons, respectively, which differ from those in the present report 9 . The study by Passias et al focused on VACTERL syndrome associated with congenital spinal abnormalities; thus, the difference in study results might be related to the use of different codes for reimbursement in the International Classification of Disease, Ninth Revision, and Clinical Modification (ICD-9-CM) formats.…”

Section: Discussioncontrasting

confidence: 88%

Incidence rate of congenital scoliosis estimated from a nationwide health insurance database

Kwon

Chae

Lee

et al. 2021

Sci Rep

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To investigate the epidemiology of congenital scoliosis (CS) and treatment trends. An age-matched, nationwide, population-based study was conducted using the National Health Insurance and Health Insurance Review and Assessment databases from 2010 to 2015. Data regarding the diagnosis and treatment of scoliosis were extracted using International Classifications of Diseases, 10th revision codes. The age-matched normal population was determined from the Korean Statistical Information Service database. We analyzed the incidence rate of CS according to age and sex, as well as the proportion of surgically treated patients. A total of 1664 patients (aged 0–19 years) were diagnosed with CS. The overall average incidence rate of CS over the 5-year period was 3.08 per 100,000 persons, with the highest and second highest rates at 0 years and 12–16 years of age, respectively. The incidence rate stratified by age ranged from 1.5 to 20.1 per 100,000 persons among the age-matched normal population, with peaks at 0 years of age and the second growth spurt in adolescence (12–16 years for males; 10–14 years for females). Anterior surgery was rarely performed; posterior surgery was performed in 92 patients (5.5% of all patients), with the highest prevalence (56.5%) in patients diagnosed at 10–14 years of age. The overall average incidence rate of CS over a 5-year period was 3.08 per 100,000 persons. Only 5.5% of patients underwent surgery within 5 years after the initial diagnosis.

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Section: Discussioncontrasting

confidence: 88%

Incidence rate of congenital scoliosis estimated from a nationwide health insurance database

Kwon

Chae

Lee

et al. 2021

Sci Rep

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“…3 Intraspinal malformations (duplication of the cord, tethered cord, or other deformities) are found in 20–40% of patients and should be treated surgically before treating the kyphosis. 1,3,23 Anterior, posterior, or combined approaches used to be done in the past to reconstruct the anterior compressive column and posterior traction column, but none of the studies confirmed which approach is the most suitable. Many surgical techniques were developed to correct kyphosis posteriorly, which are PVCR and reconstruction or shortening of the posterior column with PSO, wedge osteotomy, or decancellation of the vertebral body in addition to the posterior instrumentation.…”

Section: Discussionmentioning

confidence: 99%

Severe thoracolumbar congenital kyphosis treated with single posterior approach and gradual “in situ” correction

Audat

Radaideh

Odat

et al. 2020

J Orthop Surg (Hong Kong)

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Background: Congenital kyphosis results from the failed formation of the vertebrae during the embryonic period and may be associated with cardiac, urogenital, or spinal cord anomalies. Surgical treatment is the best choice through anterior, posterior, or both approaches. Objectives: This study aims to evaluate the effect of posterior gradual correction using the “in situ” bender to correct severe thoracolumbar congenital kyphosis with or without osteotomy or excision of the vertebra. Methods: Twenty-five patients with an age range of 2–23 (mean ± SD = 12.58 ± 6.03) years with severe thoracolumbar kyphosis were treated surgically at our institution between 2004 and 2013. Pedicle screwing, osteotomy, and gradual “in situ” bending through the single posterior approach were the choices of treatment. Cobb’s angle, patient’s height, and SRS-22r were used to evaluate the patients preoperatively and postoperatively. Follow-up periods were 35–136 months. Result: Cobb’s angle pre-surgery range was 35–180 (81.48 ± 39.1) degrees improved post-surgery to 0–45 (21.72 ± 13.47) degrees ( p-value <0.0001). The range of patients’ standing height pre-surgery was 79–170 (142.42 ± 24.85) centimeters increased after surgery to 81–175 (147.76 ± 26.33) centimeters ( p-value <0.0001). SRS-22r pre-surgery range was between 2.12 and 3.904 (3.2 ± 0.77) and improved post-surgery to 4.16 and 4.96 (4.59 ± 0.29) ( p-value = 0.046). Conclusion: Gradual correction with the “in situ” bender with or without osteotomy through the single posterior approach can give satisfying clinical (patients’ standing height and SRS-22r scores) and radiological (Cobb’s angle) results to treat severe congenital thoracolumbar kyphosis.

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“…The incidence of hemivertebra formation was reported to be 0.09 per 1000 births, and the rate of a second congenital spine anomaly was reported to be 10% 9 . If it is considered that only some of second congenital anomalies are diastematomyelia and only some of these patients develop scoliosis, one can easily say that the combination of the hemivertebra formation with diastematomyelia is quite rare.…”

Section: Discussionmentioning

confidence: 99%

Excision and short segment fusion of a double ipsilateral lumbar hemivertebrae associated with a diastematomyelia and fixed pelvic obliquity

Şenköylü

Çetinkaya

Aktaş

et al. 2019

Acta Orthopaedica et Traumatologica Turcica

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We report the surgical treatment course of a 4-year-old girl with congenital scoliosis, diastematomyelia and double adjacent hemivertebrae. She had a lumbar curve with an apparent pelvic obliquity. Simultaneous excision of double segmented sequential hemivertebra at the L3–L4 level and fusion with short-segment instrumentation was performed via a posterior approach. Intraoperative radiographs revealed satisfactory curve correction and 0° pelvic obliquity. Following the excision of double adjacent hemivertebrae, three adjacent nerve roots were placed in one intervertebral foramen bilaterally. Nevertheless, no neurological deficit was developed, and the patient was able to ambulate with a brace at day one. Pelvic balance and deformity correction were maintained with no implant failure at the fifth year follow-up. Excision of two ipsilateral adjacent hemivertebra and short-segment posterior fusion performed via posterior-only approach simultaneously is an effective, safe, and less invasive technique for the treatment of the described case.

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Incidence of Congenital Spinal Abnormalities Among Pediatric Patients and Their Association With Scoliosis and Systemic Anomalies

Abstract: Level III.

Cited by 44 publications

References 28 publications

Incidence rate of congenital scoliosis estimated from a nationwide health insurance database

Incidence rate of congenital scoliosis estimated from a nationwide health insurance database

Severe thoracolumbar congenital kyphosis treated with single posterior approach and gradual “in situ” correction

Excision and short segment fusion of a double ipsilateral lumbar hemivertebrae associated with a diastematomyelia and fixed pelvic obliquity

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